PBGD Antibody (B-6): sc-166788
- PBGD Antibody (B-6) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 321-337 near the C-terminus of PBGD of human origin
- recommended for detection of PBGD of human origin by WB, IP, IF, IHC(P) and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for PBGD Antibody (B-6) for WB and IHC(P) applications. These reagents are now offered in bundles with PBGD Antibody (B-6) (see ordering information below).
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PBGD Antibody (B-6) is a mouse monoclonal IgG1 antibody that detects porphobilinogen deaminase (PBGD) in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). PBGD plays a crucial role in the heme synthesis pathway, catalyzing the conversion of porphobilinogen into hydroxymethylbilane, which is a key intermediate in the production of heme, an essential component of hemoglobin and various enzymes. Proper functioning of PBGD is vital, as deficiencies can lead to acute intermittent porphyria (AIP), a serious inherited disorder characterized by neurological dysfunctions, abdominal pain, and elevated levels of porphobilinogen and aminolevulinic acid in the urine. Understanding PBGD structure is important because multiple domains facilitate enzymatic activity and interactions with other proteins in the heme biosynthesis pathway. Integrity of these structural features is essential for maintaining normal metabolic processes, and any alterations can significantly impact heme production and lead to pathological conditions. Anti-PBGD antibody (B-6) is an invaluable tool for researchers studying PBGD implications in health and disease, providing insights into metabolic disorders and potential therapeutic targets.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PBGD Antibody (B-6) | sc-166788 | 200 µg/ml | $322.00 | |||
PBGD Antibody (B-6): m-IgG Fc BP-HRP Bundle | sc-537531 | 200 µg Ab; 10 µg BP | $361.00 | |||
PBGD Antibody (B-6): m-IgGκ BP-HRP Bundle | sc-534824 | 200 µg Ab; 40 µg BP | $361.00 | |||
PBGD Antibody (B-6): m-IgG1 BP-HRP Bundle | sc-545215 | 200 µg Ab; 20 µg BP | $361.00 | |||
PBGD (B-6) Neutralizing Peptide | sc-166788 P | 100 µg/0.5 ml | $69.00 |