Date published: 2026-4-24

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PBGD Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of PBGD monoclonal antibodies for investigating porphobilinogen deaminase (PBGD) function and biological roles. PBGD Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Porphobilinogen deaminase is a crucial enzyme in the heme biosynthesis pathway, catalyzing the conversion of porphobilinogen to hydroxymethylbilane. PBGD plays a significant role in the production of heme, which is essential for various biological processes, including oxygen transport and electron transfer in cellular respiration. Understanding PBGD function is vital for elucidating disorders related to heme metabolism, such as acute intermittent porphyria. Research into PBGD has revealed its importance in maintaining proper heme levels across different tissue types. Investigating PBGD expression patterns can provide insights into metabolic disorders and potential therapeutic approaches. PBGD research continues to uncover new aspects of heme metabolism regulation and disease mechanisms. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing scientific understanding of PBGD and its role in human health and disease.

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PBGD Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

PBGD Antibody (E-9)

sc-166743mouse IgG2a κ62-361 (h)WB, IP, IF, ELISAm, r, h

new

(2)

PBGD Antibody (B-3)

sc-166742mouse IgG1 κ62-361 (h)WB, IP, IF, ELISAm, r, h

new

(1)

PBGD Antibody (B-6)

sc-166788mouse IgG1 κC-terminal (h)WB, IP, IF, IHC(P), ELISAh
1
(3)

PBGD Antibody (H-11)

sc-166842mouse IgG2b κC-terminal (h)WB, IP, IF, ELISAm, r, h
2
(2)

PBGD CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PBGD Double Nickase Plasmid (h)

sc-404924-NIChGene KnockoutPuromycin0
(0)

PBGD Double Nickase Plasmid (h2)

sc-404924-NIC-2hGene KnockoutPuromycin0
(0)

PBGD CRISPR/Cas9 KO Plasmid (m)

sc-420870mGene KnockoutGFP0
(0)

PBGD HDR Plasmid (m)

sc-420870-HDRmHomology Directed RepairPuromycin0
(0)

PBGD CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PBGD CRISPR Activation Plasmid (m)

sc-420870-ACTmGene ActivationPuro, Blast, Hygro0
(0)

PBGD CRISPR Activation Plasmid (m2)

sc-420870-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

PBGD siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PBGD siRNA (h)

sc-45702hGene SilencingN/A0
(0)

PBGD shRNA Plasmid (h)

sc-45702-SHhGene SilencingPuromycin0
(0)

PBGD shRNA (h) Lentiviral Particles

sc-45702-VhGene SilencingPuromycin0
(0)

PBGD siRNA (m)

sc-45703mGene SilencingN/A0
(0)

PBGD shRNA Plasmid (m)

sc-45703-SHmGene SilencingPuromycin0
(0)

PBGD shRNA (m) Lentiviral Particles

sc-45703-VmGene SilencingPuromycin0
(0)