PAFAH1B2 Antibody (A-6): sc-393216
- PAFAH1B2 Antibody (A-6) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 10-31 near the N-terminus of PAFAH1B2 of human origin
- recommended for detection of PAFAH1B2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for PAFAH1B2 Antibody (A-6) for WB applications. These reagents are now offered in bundles with PAFAH1B2 Antibody (A-6) (see ordering information below).
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PAFAH1B2 Antibody (A-6) is a mouse monoclonal IgG2a antibody that detects PAFAH1B2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PAFAH1B2, also known as platelet-activating factor acetylhydrolase IB subunit beta, is a 229 amino acid cytoplasmic protein that plays a crucial role in lipid metabolism by inactivating platelet-activating factor (PAF), a potent inflammatory mediator, through the removal of its acetyl group at the sn-2 position. This enzymatic activity is vital for regulating inflammatory responses and maintaining cellular homeostasis, as excessive PAF can lead to pathological conditions such as asthma and cardiovascular diseases. PAFAH1B2 is a key component of the cytosolic PAFAH1B heterotrimeric complex, which also includes alpha and gamma subunits, and is encoded by a gene located on human chromosome 11q23.3, a region associated with various genetic disorders. The ability of PAFAH1B2 to modulate PAF levels underscores its importance in both normal physiology and disease states, making PAFAH1B2 a significant target for research and therapeutic interventions. Anti-PAFAH1B2 antibody (A-6) is an essential tool for scientists investigating the role of PAFAH1B2 in various biological processes and disease mechanisms.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PAFAH1B2 Antibody (A-6) | sc-393216 | 200 µg/ml | $322.00 | |||
PAFAH1B2 Antibody (A-6): m-IgG Fc BP-HRP Bundle | sc-538168 | 200 µg Ab; 10 µg BP | $361.00 | |||
PAFAH1B2 Antibody (A-6): m-IgGκ BP-HRP Bundle | sc-535728 | 200 µg Ab; 40 µg BP | $361.00 | |||
PAFAH1B2 Antibody (A-6): m-IgG2a BP-HRP Bundle | sc-548223 | 200 µg Ab; 10 µg BP | $361.00 | |||
PAFAH1B2 (A-6) Neutralizing Peptide | sc-393216 P | 100 µg/0.5 ml | $69.00 |