p35 Antibody (C-3): sc-518010
- p35 Antibody (C-3) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 282-307 at the C-terminus of p35 of human origin
- Anti-p35 Antibody (C-3) is recommended for detection of p25 and p35 regulatory subunits of Cdk5 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-p35 Antibody (C-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for p35 Antibody (C-3) for WB and IHC(P) applications. These reagents are now offered in bundles with p35 Antibody (C-3) (see ordering information below).
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SEE ALSO...
p35 Antibody (C-3) is a mouse monoclonal IgG2b kappa light chain antibody that detects p25 and p35 regulatory subunits of Cdk5 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). anti-p35 antibody (C-3) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Cyclin-dependent kinase-5 (Cdk5) plays a crucial role in regulating neuronal functions and is essential for proper brain development and function. Cdk5 is primarily active in the brain, where p35 monoclonal antibody (C-3) targets processes such as neuronal migration, synaptic plasticity, and neurotransmitter release regulation. p35 (C-3) antibody recognizes a subunit vital for Cdk5 activation, enhancing kinase enzymatic activity and ensuring localization to neuronal cells. p35 can be cleaved to form p25, which has been implicated in neurodegenerative diseases, highlighting the significance of understanding these proteins′ regulation and function in both health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
p35 Antibody (C-3) | sc-518010 | 200 µg/ml | $322.00 | |||
p35 Antibody (C-3): m-IgGκ BP-HRP Bundle | sc-525323 | 200 µg Ab, 40 µg BP | $361.00 | |||
p35 Antibody (C-3): m-IgG2b BP-HRP Bundle | sc-549228 | 200 µg Ab; 10 µg BP | $361.00 | |||
p35 Antibody (C-3) AC | sc-518010 AC | 500 µg/ml, 25% agarose | $424.00 | |||
p35 Antibody (C-3) HRP | sc-518010 HRP | 200 µg/ml | $322.00 | |||
p35 Antibody (C-3) FITC | sc-518010 FITC | 200 µg/ml | $336.00 | |||
p35 Antibody (C-3) PE | sc-518010 PE | 200 µg/ml | $349.00 | |||
p35 Antibody (C-3) Alexa Fluor® 488 | sc-518010 AF488 | 200 µg/ml | $364.00 | |||
p35 Antibody (C-3) Alexa Fluor® 546 | sc-518010 AF546 | 200 µg/ml | $364.00 | |||
p35 Antibody (C-3) Alexa Fluor® 594 | sc-518010 AF594 | 200 µg/ml | $364.00 | |||
p35 Antibody (C-3) Alexa Fluor® 647 | sc-518010 AF647 | 200 µg/ml | $364.00 | |||
p35 Antibody (C-3) Alexa Fluor® 680 | sc-518010 AF680 | 200 µg/ml | $364.00 | |||
p35 Antibody (C-3) Alexa Fluor® 790 | sc-518010 AF790 | 200 µg/ml | $364.00 |