p22HBP Antibody (E-3): sc-398750
- p22HBP Antibody (E-3) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 26-138 mapping within an internal region of p22HBP of human origin
- p22HBP Antibody (E-3) is recommended for detection of p22HBP of human origin by WB, IP, IF and ELISA
- Anti-p22HBP Antibody (E-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for p22HBP Antibody (E-3) for WB applications. These reagents are now offered in bundles with p22HBP Antibody (E-3) (see ordering information below).
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SEE ALSO...
p22HBP Antibody (E-3) is a mouse monoclonal IgG1 kappa light chain antibody that detects p22HBP of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). p22HBP (E-3) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. p22HBP, also known as heme binding protein 1 (HEBP1), is a 189 amino acid intracellular tetrapyrrole-binding protein that plays a crucial role in cellular detoxification by sequestering free porphyrinogens, thereby preventing potential cellular toxicity. p22HBP exists as a monomer and is primarily localized in the cytoplasm, where p22HBP features a 21 amino acid chemoattractant at its N-terminus that serves as a natural ligand for the formyl peptide receptor 3 (FPR3). As a member of the HEBP family, p22HBP exhibits a strong binding affinity for N-methylprotoporphyrin and metalloporphyrins, which is significant for its function in heme metabolism and cellular homeostasis. The gene encoding p22HBP is located on human chromosome 12, a region associated with various genetic disorders, including hypochondrogenesis and Noonan syndrome, highlighting the importance of p22HBP in both normal physiology and disease states.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
p22HBP Antibody (E-3) | sc-398750 | 200 µg/ml | $322.00 | |||
p22HBP Antibody (E-3): m-IgG Fc BP-HRP Bundle | sc-530914 | 200 µg Ab; 10 µg BP | $361.00 | |||
p22HBP Antibody (E-3): m-IgGκ BP-HRP Bundle | sc-524468 | 200 µg Ab, 40 µg BP | $361.00 | |||
p22HBP Antibody (E-3): m-IgG1 BP-HRP Bundle | sc-544316 | 200 µg Ab; 20 µg BP | $361.00 | |||
p22HBP Antibody (E-3) AC | sc-398750 AC | 500 µg/ml, 25% agarose | $424.00 | |||
p22HBP Antibody (E-3) HRP | sc-398750 HRP | 200 µg/ml | $322.00 | |||
p22HBP Antibody (E-3) FITC | sc-398750 FITC | 200 µg/ml | $336.00 | |||
p22HBP Antibody (E-3) PE | sc-398750 PE | 200 µg/ml | $349.00 | |||
p22HBP Antibody (E-3) Alexa Fluor® 488 | sc-398750 AF488 | 200 µg/ml | $364.00 | |||
p22HBP Antibody (E-3) Alexa Fluor® 546 | sc-398750 AF546 | 200 µg/ml | $364.00 | |||
p22HBP Antibody (E-3) Alexa Fluor® 594 | sc-398750 AF594 | 200 µg/ml | $364.00 | |||
p22HBP Antibody (E-3) Alexa Fluor® 647 | sc-398750 AF647 | 200 µg/ml | $364.00 | |||
p22HBP Antibody (E-3) Alexa Fluor® 680 | sc-398750 AF680 | 200 µg/ml | $364.00 | |||
p22HBP Antibody (E-3) Alexa Fluor® 790 | sc-398750 AF790 | 200 µg/ml | $364.00 |