p130 Cas Antibody (C-4): sc-365200
- p130 Cas Antibody (C-4) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 147-177 within an internal region of p130 Cas of human origin
- recommended for detection of p130 Cas and LOC646079 of human origin and p130 Cas of mouse and rat origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for p130 Cas Antibody (C-4) for WB applications. These reagents are now offered in bundles with p130 Cas Antibody (C-4) (see ordering information below).
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p130 Cas Antibody (C-4) is a mouse monoclonal IgG1 antibody that detects p130 Cas in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). p130 Cas, also known as Crk-associated substrate, plays a crucial role in cellular signaling pathways, particularly in cell adhesion and migration. p130 Cas is primarily located in the cytoplasm but can translocate to the cell membrane upon tyrosine phosphorylation, which is essential for mediating signals from growth factor receptors and integrins. p130 Cas relocates to allow dynamic regulation of signaling pathways that control cellular responses to external stimuli, such as proliferation and differentiation. p130 Cas contains multiple SH2-binding motifs, making p130 Cas a key substrate for various protein tyrosine kinases, including v-Src and v-Crk, which influence phosphorylation status and subsequent cellular localization. p130 Cas monoclonal antibody (C-4) serves as an invaluable tool for researchers studying cell signaling mechanisms and p130 Cas functions in various biological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
p130 Cas Antibody (C-4) | sc-365200 | 200 µg/ml | $316.00 | |||
p130 Cas Antibody (C-4): m-IgG Fc BP-HRP Bundle | sc-537788 | 200 µg Ab; 10 µg BP | $354.00 | |||
p130 Cas Antibody (C-4): m-IgGκ BP-HRP Bundle | sc-535174 | 200 µg Ab; 40 µg BP | $354.00 | |||
p130 Cas Antibody (C-4): m-IgG1 BP-HRP Bundle | sc-545352 | 200 µg Ab; 20 µg BP | $354.00 | |||
p130 Cas (C-4) Neutralizing Peptide | sc-365200 P | 100 µg/0.5 ml | $68.00 |