P-Selectin/CD62P/SELP Antibody (Psel.KO.2.9): sc-101619

P-Selectin Antibody (Psel.KO.2.9) is a mouse monoclonal IgG1 antibody that detects P-Selectin in human and porcine samples through applications such as western blotting (WB), immunoprecipitation (IP), and flow cytometry (FCM). P-Selectin, also known as GMP-140 or CD62P, plays a crucial role in the inflammatory response by mediating the adhesion of leukocytes to activated endothelial cells and platelets, which is essential for the recruitment of immune cells to sites of injury or infection. P-Selectin is primarily located on the surface of activated platelets and endothelial cells, where P-Selectin facilitates the initial stages of leukocyte rolling and adhesion, a critical process in the immune response. The interaction of P-Selectin with its ligands, such as sialylated carbohydrates on neutrophils and monocytes, underscores P-Selectin′s importance in regulating inflammation and thrombosis. Using anti-P-Selectin antibody (Psel.KO.2.9) in your research can provide valuable insights into the mechanisms of cell adhesion and the role of P-Selectin in various pathological conditions, including cardiovascular diseases and inflammatory disorders.

The preferred P-Selectin/CD62P/SELP antibody is P-Selectin/CD62P/SELP Antibody (CTB201): sc-8419.