P-Selectin/CD62P/SELP Antibody (H-2): sc-271267

P-Selectin Antibody (H-2) is a mouse monoclonal IgG1 kappa light chain antibody that detects P-Selectin in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-P-Selectin antibody (H-2) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. P-Selectin, also known as GMP-140 or CD62P, plays a crucial role in the inflammatory response by mediating the adhesion of leukocytes to activated endothelial cells and platelets. This interaction is vital for the recruitment of immune cells to sites of injury or infection, highlighting P-Selectin′s importance in both normal immune function and pathological conditions such as thrombosis and atherosclerosis. P-Selectin is primarily located on the surface of activated platelets and endothelial cells, where P-Selectin facilitates the rolling and adhesion of leukocytes, thus contributing to the overall process of inflammation and immune response. Understanding P-Selectin′s function and dynamics is essential for developing therapeutic strategies targeting inflammatory diseases and improving our knowledge of vascular biology.

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Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-P-Selectin/CD62P/SELP Antibody (H-2) has 4 citations in a variety of scientific publications.

Primary antibodies like Anti-P-Selectin/CD62P/SELP Antibody (H-2) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

P-Selectin/CD62P/SELP Antibody (H-2) Specifications

Alternate Product Name: CD62

Product Clone Name: H-2

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 794-829

Epitope Target: P-Selectin

Epitope Species: human

Product Reactivity/Detection: P-Selectin

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: equine, canine, bovine and porcine

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 4 citations in various scientific publications

Available Conjugates/Forms for P-Selectin/CD62P/SELP Antibody (H-2): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, P: Blocking Peptide, PE: Phycoerythrin

The preferred P-Selectin/CD62P/SELP antibody is P-Selectin/CD62P/SELP Antibody (CTB201): sc-8419.