P-Selectin/CD62P/SELP Antibody (1 E 3): sc-19672

P-Selectin Antibody (1 E 3) is a mouse monoclonal IgG2a kappa light chain antibody that detects P-Selectin of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). P-Selectin (1 E 3) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. P-Selectin, also known as GMP-140 or CD62P, plays a crucial role in mediating the adhesion of platelets and leukocytes to the endothelium during inflammatory responses, which is vital for the recruitment of immune cells to sites of injury or infection. P-Selectin is primarily located on the surface of activated platelets and endothelial cells, where P-Selectin facilitates the initial stages of cell adhesion and migration. Proper functioning of P-Selectin is essential for maintaining vascular integrity and regulating immune responses, making P-Selectin a significant target for research in cardiovascular diseases and inflammatory conditions. P-Selectin interacts with specific carbohydrates on neutrophils and monocytes, and P-Selectin expression is upregulated in response to inflammatory stimuli, highlighting P-Selectin′s importance in the pathophysiology of various diseases.

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Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-P-Selectin/CD62P/SELP Antibody (1 E 3) has 13 citations in a variety of scientific publications.

Primary antibodies like Anti-P-Selectin/CD62P/SELP Antibody (1 E 3) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

P-Selectin/CD62P/SELP Antibody (1 E 3) Specifications

Alternate Product Name: CD62

Product Clone Name: 1 E 3

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids:

Epitope Target: P-Selectin

Epitope Species: human

Product Reactivity/Detection: P-Selectin

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), FCM

Vialing Information: Each vial contains 200 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 13 citations in various scientific publications

Available Conjugates/Forms for P-Selectin/CD62P/SELP Antibody (1 E 3): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin

The preferred P-Selectin/CD62P/SELP antibody is P-Selectin/CD62P/SELP Antibody (CTB201): sc-8419.