Date published: 2025-10-16

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NURIM Antibody (E-11): sc-514010

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Datasheets
  • NURIM Antibody (E-11) is a mouse monoclonal IgG2b κ NURIM antibody provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 28-47 near the N-terminus of NURIM of human origin
  • NURIM Antibody (E-11) is recommended for detection of NURIM isoforms 1-5 of mouse, rat and human origin by WB, IP, IF and ELISA
  • Anti-NURIM Antibody (E-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
  • also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for NURIM Antibody (E-11) for WB applications. These reagents are now offered in bundles with NURIM Antibody (E-11) (see ordering information below).

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    SEE ALSO...

    NURIM Antibody (E-11) is a mouse monoclonal IgG2b kappa light chain antibody that detects NURIM protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). NURIM (E-11) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. NURIM protein, also known as NRM or NRM29, is a 262 amino acid multi-pass membrane protein primarily localized to the inner membrane of the nucleus, which is crucial for maintaining nuclear integrity and regulating the transport of molecules between the nucleus and cytoplasm. This localization plays a vital role in nuclear envelope dynamics, influencing processes such as cell division and gene expression. NURIM is encoded on human chromosome 6, a region associated with various health conditions, including early onset intestinal cancer and several neurodegenerative and psychiatric disorders. Multiple alternatively spliced isoforms of NURIM suggest a complex regulatory mechanism that may contribute to enzymatic functions, further underscoring importance in cellular processes.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    NURIM Antibody (E-11) References:

    1. A visual screen of a GFP-fusion library identifies a new type of nuclear envelope membrane protein.  |  Rolls, MM., et al. 1999. J Cell Biol. 146: 29-44. PMID: 10402458
    2. Inner nuclear membrane proteins: functions and targeting.  |  Holmer, L. and Worman, HJ. 2001. Cell Mol Life Sci. 58: 1741-7. PMID: 11766875
    3. Analysis of the localization and topology of nurim, a polytopic protein tightly associated with the inner nuclear membrane.  |  Hofemeister, H. and O'Hare, P. 2005. J Biol Chem. 280: 2512-21. PMID: 15542857
    4. Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.  |  Otsuki, T., et al. 2005. DNA Res. 12: 117-26. PMID: 16303743
    5. Rapid evolution of major histocompatibility complex class I genes in primates generates new disease alleles in humans via hitchhiking diversity.  |  Shiina, T., et al. 2006. Genetics. 173: 1555-70. PMID: 16702430
    6. Early sorting of inner nuclear membrane proteins is conserved.  |  Braunagel, SC., et al. 2007. Proc Natl Acad Sci U S A. 104: 9307-12. PMID: 17517639

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    NURIM Antibody (E-11)

    sc-514010
    200 µg/ml
    $316.00

    NURIM Antibody (E-11): m-IgG Fc BP-HRP Bundle

    sc-531000
    200 µg Ab; 10 µg BP
    $354.00

    NURIM Antibody (E-11): m-IgGκ BP-HRP Bundle

    sc-524570
    200 µg Ab, 40 µg BP
    $354.00

    NURIM Antibody (E-11): m-IgG2b BP-HRP Bundle

    sc-550247
    200 µg Ab; 10 µg BP
    $354.00

    NURIM Antibody (E-11) AC

    sc-514010 AC
    500 µg/ml, 25% agarose
    $416.00

    NURIM Antibody (E-11) HRP

    sc-514010 HRP
    200 µg/ml
    $316.00

    NURIM Antibody (E-11) FITC

    sc-514010 FITC
    200 µg/ml
    $330.00

    NURIM Antibody (E-11) PE

    sc-514010 PE
    200 µg/ml
    $343.00

    NURIM Antibody (E-11) Alexa Fluor® 488

    sc-514010 AF488
    200 µg/ml
    $357.00

    NURIM Antibody (E-11) Alexa Fluor® 546

    sc-514010 AF546
    200 µg/ml
    $357.00

    NURIM Antibody (E-11) Alexa Fluor® 594

    sc-514010 AF594
    200 µg/ml
    $357.00

    NURIM Antibody (E-11) Alexa Fluor® 647

    sc-514010 AF647
    200 µg/ml
    $357.00

    NURIM Antibody (E-11) Alexa Fluor® 680

    sc-514010 AF680
    200 µg/ml
    $357.00

    NURIM Antibody (E-11) Alexa Fluor® 790

    sc-514010 AF790
    200 µg/ml
    $357.00

    NURIM (E-11) Neutralizing Peptide

    sc-514010 P
    100 µg/0.5 ml
    $68.00

    What application is the blocking peptide sc-514010 P appropriate for?

    Asked by: TinTin
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-03-01
    • y_2025, m_10, d_14, h_6CST
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    Rated 5 out of 5 by from Satisfactory Western blot data of NURIM expressionSatisfactory Western blot data of NURIM expression in non-transfected 293T, mouse NURIM transfected 293T and PC-3 whole cell lysates, PC-3 and IMR-32 nuclear extracts and human testis tissue extract . -SCBT QC
    Date published: 2014-11-02
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    NURIM Antibody (E-11) is rated 5.0 out of 5 by 1.
    • y_2025, m_10, d_14, h_6
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