NPP6 Antibody (G-9): sc-373900
- NPP6 Antibody (G-9) is a mouse monoclonal IgM κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 53-81 within an N-terminal extracellular domain of NPP6 of human origin
- recommended for detection of NPP6 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and canine, bovine and porcine
- m-IgGκ BP-HRP is the preferred secondary detection reagent for NPP6 Antibody (G-9) for WB and IHC(P) applications. This reagent is now offered in a bundle with NPP6 Antibody (G-9) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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NPP6 Antibody (G-9) is a mouse monoclonal IgM antibody that detects NPP6 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). NPP6, also known as ectonucleotide pyrophosphatase/phosphodiesterase family member 6, is a 440 amino acid protein that plays a crucial role in lipid metabolism as a choline-specific glycerophosphodiester phosphodiesterase. NPP6′s ability to hydrolyze substrates such as lysophosphatidylcholine, which is important for cell signaling and membrane integrity, highlights NPP6′s significance in maintaining cellular homeostasis. Predominantly expressed in the brain and kidney, NPP6 is a secreted and single-pass type I membrane protein that contributes to the regulation of lipid levels in these tissues. The gene encoding NPP6 is located on human chromosome 4, a region associated with several genetic disorders, including Huntington′s disease and polycystic kidney disease, underscoring the potential implications of NPP6 in various pathophysiological conditions. With diverse applications and critical biological functions, anti-NPP6 antibody (G-9) is an essential tool for researchers investigating lipid metabolism and related diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NPP6 Antibody (G-9) | sc-373900 | 200 µg/ml | $316.00 | |||
NPP6 Antibody (G-9): m-IgGκ BP-HRP Bundle | sc-535334 | 200 µg Ab; 40 µg BP | $354.00 | |||
NPP6 (G-9) Neutralizing Peptide | sc-373900 P | 100 µg/0.5 ml | $68.00 |