NgR3 Antibody (B-7): sc-398584

NgR3 Antibody (B-7) is a mouse monoclonal IgG2a antibody that detects NgR3 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). NgR3, also known as Nogo-66 receptor-related protein 3 or RTN4RL1, is a 441 amino acid protein belonging to the Nogo receptor family, characterized by eight leucine-rich repeats. NgR3 is primarily localized to the cell membrane of neurons in the brain, where NgR3 plays a crucial role in regulating axonal regeneration and plasticity within the adult central nervous system. NgR3′s ability to modulate neuronal responses is vital for understanding recovery mechanisms following neural injuries, as NgR3 influences the growth and repair of axons. Additionally, NgR3 is expressed at lower levels in various tissues, including the lung, placenta, kidney, mammary gland, skeletal muscle, spleen, and salivary gland, indicating potential involvement in diverse physiological processes. The gene encoding NgR3 is located on human chromosome 17, which comprises over 2.5% of the human genome, containing approximately 81 million bases that encode more than 1,200 genes. anti-NgR3 antibody (B-7) is an essential tool for researchers investigating the complex roles of NgR3 in neurobiology and regenerative medicine.

The preferred NgR3 antibody is NgR3 Antibody (H-11): sc-515400.