
NCAM Antibody (D-10) is a mouse monoclonal IgG2a kappa light chain antibody specifically designed to target the Neural Cell Adhesion Molecule (NCAM), also known as CD56. anti-NCAM antibody (D-10) is raised against amino acids 1-300 at the N-terminus of human NCAM, ensuring precise recognition and binding. NCAM (D-10) antibody is highly effective for detecting human NCAM in various applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). NCAM is a vital cell surface glycoprotein involved in mediating cell-to-cell interactions, playing a crucial role in embryogenesis, neural development, and synaptic plasticity. NCAM facilitates important biological processes such as neurite outgrowth and neuronal differentiation by interacting with proteins like fibroblast growth factor receptors (FGFRs), integrins, and intracellular signaling molecules such as Fyn and focal adhesion kinase (FAK). Beyond its essential functions in normal physiology, NCAM is a significant marker in various human tumors, including neuroblastomas, rhabdomyosarcomas, Wilms′ tumor, and Ewing′s sarcoma. NCAM (D-10) monoclonal antibody is an invaluable tool for researchers studying the molecular mechanisms underlying neural development and tumor biology, providing reliable detection and analysis of NCAM expression. anti-NCAM antibody (D-10) supports advancements in both developmental biology and cancer research by facilitating the investigation of NCAM interactions and signaling pathways.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NCAM/CD56 Antibody (D-10) | sc-374289 | 200 µg/ml | $322.00 | |||
NCAM/CD56 Antibody (D-10): m-IgG Fc BP-HRP Bundle | sc-537949 | 200 µg Ab; 10 µg BP | $361.00 | |||
NCAM/CD56 Antibody (D-10): m-IgGκ BP-HRP Bundle | sc-535437 | 200 µg Ab; 40 µg BP | $361.00 | |||
NCAM/CD56 Antibody (D-10): m-IgG2a BP-HRP Bundle | sc-548157 | 200 µg Ab; 10 µg BP | $361.00 |