NCAM/CD56 Antibody (B332): sc-73555
- NCAM/CD56 Antibody (B332) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against NCAM of human origin
- recommended for detection of NCAM of mouse, rat and human origin by WB, IP, IF, IHC(P) and FCM; also recommended for detection of neuroectodermally derived tumors such as neuroblastoma, medulloblastoma, astrocytoma and retinoblastoma
- available conjugated to phycoerythrin for IF, IHC(P) and FCM
- See NCAM/CD56 (123C3): sc-7326 for NCAM/CD56 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for NCAM/CD56 Antibody (B332) for WB and IHC(P) applications. These reagents are now offered in bundles with NCAM/CD56 Antibody (B332) (see ordering information below).
NCAM Antibody (B332) is a mouse monoclonal IgG1 kappa light chain antibody specifically engineered to recognize the human Neural Cell Adhesion Molecule (NCAM), also known as CD56 or NCAM1. NCAM is a critical cell surface glycoprotein located on the plasma membrane, playing a pivotal role in cell-to-cell interactions essential for neural development, synaptic plasticity, and the maintenance of neural networks. Anti-NCAM antibody (B332) undergoes significant post-translational modifications, including glycosylation and polysialylation, which are crucial for regulating its adhesive properties and modulating its function in neural plasticity and cell migration. NCAM monoclonal antibody (B332) effectively detects NCAM from mouse, rat, and human origins, making it versatile for various experimental applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). NCAM (B332) antibody is an invaluable tool for researching neuroectodermally derived tumors like neuroblastoma, medulloblastoma, astrocytoma, and retinoblastoma, where NCAM expression is prominently observed. Anti-NCAM antibody (B332) facilitates the investigation of molecular mechanisms underlying cell adhesion, neural network formation, and the progression of neuro-related cancers. Additionally, NCAM exists in multiple isoforms generated through alternative splicing and polyadenylation of a single gene located at chromosome 11q23, contributing to its diverse functional roles in both healthy and diseased states. NCAM (B332) monoclonal antibody reliably detects these isoforms, enhancing its utility in advanced neurobiological and oncological studies, supporting a wide range of experimental and diagnostic applications.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NCAM/CD56 Antibody (B332) | sc-73555 | 200 µg/ml | $322.00 | |||
NCAM/CD56 Antibody (B332): m-IgG Fc BP-HRP Bundle | sc-537223 | 200 µg Ab; 10 µg BP | $361.00 | |||
NCAM/CD56 Antibody (B332): m-IgGκ BP-HRP Bundle | sc-534436 | 200 µg Ab; 40 µg BP | $361.00 | |||
NCAM/CD56 Antibody (B332): m-IgG1 BP-HRP Bundle | sc-545089 | 200 µg Ab; 20 µg BP | $361.00 | |||
NCAM/CD56 Antibody (B332) PE | sc-73555 PE | 200 µg/ml | $349.00 |