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Muscle FBPase Antibody (G-1) is a mouse monoclonal IgG3 antibody that detects muscle FBPase in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Muscle FBPase (G-1) antibody recognizes the protein encoded by the FBP2 gene, which plays a crucial role in carbohydrate metabolism by catalyzing the conversion of fructose-1,6-bisphosphate into fructose 6-phosphate and inorganic phosphate, a key step in gluconeogenesis and glycolysis. Anti-muscle FBPase antibody (G-1) targets an enzyme predominantly located in muscle tissue, where muscle FBPase is essential for maintaining energy homeostasis during periods of fasting or intense exercise. Proper functioning of muscle FBPase is vital, as deficiencies can lead to metabolic disorders, including hypoglycemia and metabolic acidosis, particularly in individuals with mutations in the FBP2 gene. Muscle FBPase (G-1) monoclonal antibody provides a reliable tool for researchers studying the regulation and function of this important enzyme, facilitating insights into metabolic pathways and potential therapeutic targets for related disorders.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
muscle FBPase Antibody (G-1) | sc-271799 | 200 µg/ml | $316.00 | |||
muscle FBPase Antibody (G-1): m-IgGκ BP-HRP Bundle | sc-535044 | 200 µg Ab; 40 µg BP | $354.00 | |||
muscle FBPase Antibody (G-1): m-IgG3 BP-HRP Bundle | sc-550304 | 200 µg Ab; 40 µg BP | $354.00 | |||
muscle FBPase (G-1) Neutralizing Peptide | sc-271799 P | 100 µg/0.5 ml | $68.00 |