Date published: 2026-5-25

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muscle FBPase Substrates

Santa Cruz Biotechnology now offers a broad range of muscle FBPase Substrates for use in various applications. Muscle fructose-1,6-bisphosphatase (FBPase) is an enzyme that plays a key role in gluconeogenesis, the metabolic pathway that generates glucose from non-carbohydrate precursors. This enzyme specifically catalyzes the hydrolysis of fructose-1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate, a crucial step in the regulation of glucose production in muscle tissues. Muscle FBPase is important in maintaining glucose homeostasis, especially during periods of fasting or intense exercise when the demand for glucose is high. Muscle FBPase Substrates are essential tools in scientific research, enabling researchers to study the enzyme's activity and its role in metabolic regulation within muscle cells. By utilizing these substrates, scientists can explore the dynamics of gluconeogenesis in muscle tissues, investigate the enzyme's regulatory mechanisms, and assess its contribution to overall energy metabolism. These substrates are widely used in biochemical assays to measure FBPase activity, in studies aimed at understanding the metabolic shifts that occur during exercise, and in research focused on metabolic disorders such as diabetes and muscle-wasting conditions where gluconeogenesis may be altered. The availability of these substrates has significantly advanced research in metabolism, physiology, and biochemistry, providing critical insights into the complex processes that regulate energy production and utilization in muscle tissues. View detailed information on our available muscle FBPase Substrates by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

D-Fructose 1,6-bisphosphate trisodium salt octahydrate

81028-91-3sc-221476
sc-221476A
1 g
5 g
$57.00
$97.00
1
(1)

D-Fructose 1,6-bisphosphate trisodium salt octahydrate acts as a crucial allosteric regulator in glycolysis, enhancing the activity of fructose-1,6-bisphosphatase. Its unique tri-sodium salt form increases solubility, facilitating rapid diffusion in cellular environments. The compound's ability to stabilize enzyme conformations promotes efficient substrate binding, influencing metabolic flux. Additionally, its octahydrate structure contributes to hydration dynamics, impacting reaction kinetics and enzyme interactions.