Mucin 2/MUC2 Antibody (994/152): sc-59956
- Mucin 2/MUC2 Antibody (994/152) is a mouse monoclonal IgG1 κ, cited in 3 publications, provided at 200 µg/ml
- raised against a synthetic peptide corresponding to the tandam repeat sequence of Mucin 2 of human origin
- recommended for detection of Mucin 2 of human origin by IFIHC(P)ELISA; non cross-reactive with Muc 1 or 4
- See Mucin 2/MUC2 (F-2): sc-515032 for Mucin 2/MUC2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Mucin 2/MUC2 Antibody (994/152) for IHC(P) applications. These reagents are now offered in bundles with Mucin 2/MUC2 Antibody (994/152) (see ordering information below).
Mucin 2 Antibody (994/152) is a mouse monoclonal IgG1 antibody that detects Mucin 2 in human samples through applications such as immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Mucin 2 plays a crucial role in maintaining the integrity of epithelial surfaces, particularly in the intestines and airways, where Mucin 2 forms a protective mucus layer that traps pathogens and particulates, thereby preventing infection and inflammation. Mucin 2 (994/152) antibody enables researchers to study proper functioning of Mucin 2 in gut health, as Mucin 2 not only facilitates the movement of food through the digestive tract but also serves as a barrier against harmful microorganisms. Aberrant expression of Mucin 2 has been linked to various colonic tumors, highlighting Mucin 2′s importance in cancer research and diagnostics. Anti-Mucin 2 antibody (994/152) is an essential tool for researchers studying the role of mucins in health and disease, providing insights into their expression patterns and potential implications in tumorigenesis.
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LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Mucin 2/MUC2 Antibody (994/152) References:
- Characterisation of combinatorial libraries of mucin-2 antigen peptides by high-resolution mass spectrometry. | Windberg, E., et al. 2002. Rapid Commun Mass Spectrom. 16: 834-9. PMID: 11948813
- Suppression of mucin 2 enhances the proliferation and invasion of LS174T human colorectal cancer cells. | Bu, X., et al. 2011. Cell Biol Int. 35: 1121-9. PMID: 21605079
- Effect of supplemental L-threonine on mucin 2 gene expression and intestine mucosal immune and digestive enzymes activities of laying hens in environments with high temperature and humidity. | Azzam, MM., et al. 2011. Poult Sci. 90: 2251-6. PMID: 21934007
- Fatty acid synthase modulates intestinal barrier function through palmitoylation of mucin 2. | Wei, X., et al. 2012. Cell Host Microbe. 11: 140-52. PMID: 22341463
- Suppression of mucin 2 promotes interleukin-6 secretion and tumor growth in an orthotopic immune-competent colon cancer animal model. | Shan, YS., et al. 2014. Oncol Rep. 32: 2335-42. PMID: 25322805
- Assessment of cytology and mucin 2 in colorectal mucus collected from patients with inflammatory bowel disease: Results of a pilot trial. | Loktionov, A., et al. 2016. J Gastroenterol Hepatol. 31: 326-33. PMID: 26248500
- The Muc2 mucin coats murine Paneth cell granules and facilitates their content release and dispersion. | Stahl, M., et al. 2018. Am J Physiol Gastrointest Liver Physiol. 315: G195-G205. PMID: 29698056
- Lactobacillus rhamnosus GG supernatant promotes intestinal mucin production through regulating 5-HT4R and gut microbiota. | Gu, Y., et al. 2022. Food Funct. 13: 12144-12155. PMID: 36326009
- Sex drives colonic mucin sialylation in wild mice. | Bennett, AR., et al. 2024. Sci Rep. 14: 6954. PMID: 38521809
- Sishen Wan enhances intestinal barrier function via regulating endoplasmic reticulum stress to improve mice with diarrheal irritable bowel syndrome. | Zhao, Y., et al. 2024. Phytomedicine. 129: 155541. PMID: 38579640
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Mucin 2/MUC2 Antibody (994/152) | sc-59956 | 200 µg/ml | $322.00 | |||
Mucin 2/MUC2 Antibody (994/152): m-IgG Fc BP-HRP Bundle | sc-537173 | 200 µg Ab; 10 µg BP | $361.00 | |||
Mucin 2/MUC2 Antibody (994/152): m-IgGκ BP-HRP Bundle | sc-534372 | 200 µg Ab; 40 µg BP | $361.00 | |||
Mucin 2/MUC2 Antibody (994/152): m-IgG1 BP-HRP Bundle | sc-545053 | 200 µg Ab; 20 µg BP | $361.00 |