MRP2 Antibody (B-11): sc-518047
- MRP2 Antibody (B-11) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 212-236 within an internal region of MRP2 of human origin
- recommended for detection of MRP2 of human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for MRP2 Antibody (B-11) for WB applications. These reagents are now offered in bundles with MRP2 Antibody (B-11) (see ordering information below).
MRP2 Antibody (B-11) is a mouse monoclonal IgG2b light chain antibody that detects MRP2 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). MRP2, also known as the canalicular multispecific organic anion transporter, plays a crucial role in the excretion of various organic anions, including drugs and toxins, from hepatocytes into bile, thereby contributing to the detoxification processes in the liver. MRP2 is predominantly localized to the apical membrane of hepatocytes, where high expression is essential for maintaining bile flow and preventing the accumulation of potentially harmful substances within the liver. Proper functioning of MRP2 is vital for drug metabolism and clearance, and dysfunction can lead to drug-induced liver injury and cholestasis, highlighting its importance in pharmacology and toxicology. Anti-MRP2 antibody (B-11) is an invaluable tool for researchers studying multidrug resistance and liver function, providing insights into the mechanisms of drug transport and the potential implications for therapeutic interventions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MRP2 Antibody (B-11) | sc-518047 | 200 µg/ml | $316.00 | |||
MRP2 Antibody (B-11): m-IgG Fc BP-HRP Bundle | sc-538847 | 200 µg Ab; 10 µg BP | $354.00 | |||
MRP2 Antibody (B-11): m-IgGκ BP-HRP Bundle | sc-536531 | 200 µg Ab; 40 µg BP | $354.00 | |||
MRP2 Antibody (B-11): m-IgG2b BP-HRP Bundle | sc-549994 | 200 µg Ab; 10 µg BP | $354.00 |