MOBKL2A Antibody (H-3): sc-398531
- MOBKL2A Antibody (H-3) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 104-146 mapping within an internal region of MOBKL2A of human origin
- Anti-MOBKL2A Antibody (H-3) is recommended for detection of MOBKL2A of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-MOBKL2A Antibody (H-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for MOBKL2A Antibody (H-3) for WB applications. These reagents are now offered in bundles with MOBKL2A Antibody (H-3) (see ordering information below).
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MOBKL2A Antibody (H-3) is a mouse monoclonal IgG1 kappa light chain antibody that detects MOBKL2A in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-MOBKL2A antibody (H-3) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. MOBKL2A, also known as Mps one binder kinase activator-like 2A or MOB-LAK, is a 217 amino acid protein that plays a crucial role in regulating kinase activity, which is essential for various cellular processes, including cell division, growth, and signaling pathways. MOBKL2A belongs to the MOB1/phocein family and is encoded by a gene located on human chromosome 19, a region known for its high gene density and involvement in several genetic disorders. Proper functioning of MOBKL2A is vital, as dysregulation can lead to aberrant kinase activity, potentially contributing to various diseases, including cancer. Understanding MOBKL2A interactions and regulatory mechanisms can provide insights into cellular signaling roles and implications in health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
MOBKL2A Antibody (H-3) References:
- C-CAM1, a candidate tumor suppressor gene, is abnormally expressed in primary lung cancers. | Wang, L., et al. 2000. Clin Cancer Res. 6: 2988-93. PMID: 10955775
- The genomic context of natural killer receptor extended gene families. | Trowsdale, J., et al. 2001. Immunol Rev. 181: 20-38. PMID: 11513141
- Complete germline deletion of the STK11 gene in a family with Peutz-Jeghers syndrome. | Le Meur, N., et al. 2004. Eur J Hum Genet. 12: 415-8. PMID: 14970844
- Comparative human-mouse-rat sequence analysis of the ICAM gene cluster on HSA 19p13.2 and a 185-kb porcine region from SSC 2q. | Leeb, T. and Müller, M. 2004. Gene. 343: 239-44. PMID: 15588578
- The extended human leukocyte receptor complex: diverse ways of modulating immune responses. | Barrow, AD. and Trowsdale, J. 2008. Immunol Rev. 224: 98-123. PMID: 18759923
- Gene organization of the pregnancy-specific glycoprotein region on human chromosome 19: assembly and analysis of a 700-kb cosmid contig spanning the region. | Olsen, A., et al. 1994. Genomics. 23: 659-68. PMID: 7851895
- The pregnancy-specific glycoprotein (PSG) gene cluster on human chromosome 19: fine structure of the 11 PSG genes and identification of 6 new genes forming a third subgroup within the carcinoembryonic antigen (CEA) family. | Teglund, S., et al. 1994. Genomics. 23: 669-84. PMID: 7851896
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MOBKL2A Antibody (H-3) | sc-398531 | 200 µg/ml | $322.00 | |||
MOBKL2A Antibody (H-3): m-IgG Fc BP-HRP Bundle | sc-530836 | 200 µg Ab; 10 µg BP | $361.00 | |||
MOBKL2A Antibody (H-3): m-IgGκ BP-HRP Bundle | sc-524382 | 200 µg Ab, 40 µg BP | $361.00 | |||
MOBKL2A Antibody (H-3) AC | sc-398531 AC | 500 µg/ml, 25% agarose | $424.00 | |||
MOBKL2A Antibody (H-3) HRP | sc-398531 HRP | 200 µg/ml | $322.00 | |||
MOBKL2A Antibody (H-3) FITC | sc-398531 FITC | 200 µg/ml | $336.00 | |||
MOBKL2A Antibody (H-3) PE | sc-398531 PE | 200 µg/ml | $349.00 | |||
MOBKL2A Antibody (H-3) Alexa Fluor® 488 | sc-398531 AF488 | 200 µg/ml | $364.00 | |||
MOBKL2A Antibody (H-3) Alexa Fluor® 546 | sc-398531 AF546 | 200 µg/ml | $364.00 | |||
MOBKL2A Antibody (H-3) Alexa Fluor® 594 | sc-398531 AF594 | 200 µg/ml | $364.00 | |||
MOBKL2A Antibody (H-3) Alexa Fluor® 647 | sc-398531 AF647 | 200 µg/ml | $364.00 | |||
MOBKL2A Antibody (H-3) Alexa Fluor® 680 | sc-398531 AF680 | 200 µg/ml | $364.00 | |||
MOBKL2A Antibody (H-3) Alexa Fluor® 790 | sc-398531 AF790 | 200 µg/ml | $364.00 |