Anti-MCCB Antibody (B-1) is a mouse monoclonal IgG2b (kappa light chain) MCCB antibody provided at 200 µg/ml
raised against amino acids 241-540 mapping near the C-terminus of MCCB of human origin
Anti-MCCB Antibody (B-1) is recommended for detection of MCCB of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
Anti-MCCB Antibody (B-1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of MCCB (B-1): sc-390836.
m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for MCCB Antibody (B-1) for WB and IHC(P) applications. These reagents are now offered in bundles with MCCB Antibody (B-1) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
MCCB Antibody (B-1) is a high quality monoclonal MCCB antibody (also designated MCCB antibody) suitable for the detection of the MCCB protein of mouse, rat and human origin. MCCB Antibody (B-1) is available as both the non-conjugated anti-MCCB antibody form, as well as multiple conjugated forms of anti-MCCB antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Methylcrotonoly-CoA carboxylase beta chain, or MCCB, is the non-biotin containing subunit of the MCC enzyme. The deduced 563-amino acid polypeptide contains an N-terminal mitochondrial targeting sequence. MCCB is a putative dodecamer composed of six biotin-containing alpha subunits and six beta subunits. MCCB plays a role in leucine catabolism, and catalyzes the conversion of 3-methylcrotonoyl-CoA to 3-methylglutaconyl-CoA, using ATP as an energy source. Defects in the MCCC2 gene which encodes MCCB causes 3-methylcrotonylglycinuria type II (MCGII), a recessive disease characterized by muscular hypotonia and atrophy, probably of spinal origin. The MCCC2 gene maps to chromosome 5q13.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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