Mammaglobin A Antibody (F-5): sc-515195
- Mammaglobin A Antibody (F-5) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 48-93 mapping at the C-terminus of Mammaglobin A of human origin
- Mammaglobin A Antibody (F-5) is recommended for detection of Mammaglobin A of human origin by WB, IP, IF and ELISA
- Anti-Mammaglobin A Antibody (F-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Mammaglobin A Antibody (F-5) for WB applications. These reagents are now offered in bundles with Mammaglobin A Antibody (F-5) (see ordering information below).
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Mammaglobin A Antibody (F-5) is a mouse monoclonal IgG1 kappa light chain antibody that detects Mammaglobin A of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Mammaglobin A (F-5) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Mammaglobin A, also known as MGB1 and secretoglobin, family 2A, member 2 (SCGB2A2), plays a crucial role in breast tissue development and breast cancer progression. Mammaglobin A is primarily located in mammary gland epithelial cell cytoplasm, where Mammaglobin A contributes to protein and lipid secretion for milk formation. Mammaglobin A expression in breast tissue serves as a reliable diagnostic marker for breast tumors, showing increased levels in malignant tissues. Mammaglobin A belongs to the secretoglobin family of small secreted proteins that form multimeric complexes involved in immune response and tissue remodeling. As a biomarker for breast cancer, anti-Mammaglobin A antibody (F-5) provides an essential tool for researchers and clinicians studying breast cancer and related conditions.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Mammaglobin A Antibody (F-5) References:
- Mammaglobin-A is a tumor-associated antigen in human breast carcinoma. | Tanaka, Y., et al. 2003. Surgery. 133: 74-80. PMID: 12563241
- Mammaglobin: a candidate diagnostic marker for breast cancer. | Zehentner, BK. and Carter, D. 2004. Clin Biochem. 37: 249-57. PMID: 15003725
- A mammaglobin-A targeting agent for noninvasive detection of breast cancer metastasis in lymph nodes. | Tafreshi, NK., et al. 2011. Cancer Res. 71: 1050-9. PMID: 21169406
- Human mammaglobin: a superior marker for reverse-transcriptase PCR in detecting circulating tumor cells in breast cancer patients. | Li, G., et al. 2011. Biomark Med. 5: 249-60. PMID: 21473729
- Mammaglobin-A cDNA vaccination of breast cancer patients induces antigen-specific cytotoxic CD4+ICOShi T cells. | Tiriveedhi, V., et al. 2013. Breast Cancer Res Treat. 138: 109-18. PMID: 22678162
- Human mammaglobin in breast cancer: a brief review of its clinical utility. | Al Joudi, FS. 2014. Indian J Med Res. 139: 675-85. PMID: 25027076
- Developing a clinical development paradigm for translation of a mammaglobin-A DNA vaccine. | Li, L., et al. 2015. Immunotherapy. 7: 709-11. PMID: 26250406
- Mammaglobin-A is a target for breast cancer vaccination. | Kim, SW., et al. 2016. Oncoimmunology. 5: e1069940. PMID: 27057470
- Mammaglobin-A, VEGFR3, and Ki67 in Human Breast Cancer Pathology and Five Year Survival. | Baker, E., et al. 2019. Breast Cancer (Auckl). 13: 1178223419858957. PMID: 31263371
- Identification and characterization of mammaglobin-A epitope in heterogenous breast cancers for enhancing tumor-targeting therapy. | Liu, Z., et al. 2020. Signal Transduct Target Ther. 5: 82. PMID: 32467564
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Mammaglobin A Antibody (F-5) | sc-515195 | 200 µg/ml | $322.00 | |||
Mammaglobin A Antibody (F-5): m-IgG Fc BP-HRP Bundle | sc-531307 | 200 µg Ab; 10 µg BP | $361.00 | |||
Mammaglobin A Antibody (F-5): m-IgGκ BP-HRP Bundle | sc-524965 | 200 µg Ab, 40 µg BP | $361.00 | |||
Mammaglobin A Antibody (F-5): m-IgG1 BP-HRP Bundle | sc-544477 | 200 µg Ab; 20 µg BP | $361.00 | |||
Mammaglobin A Antibody (F-5) AC | sc-515195 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Mammaglobin A Antibody (F-5) HRP | sc-515195 HRP | 200 µg/ml | $322.00 | |||
Mammaglobin A Antibody (F-5) FITC | sc-515195 FITC | 200 µg/ml | $336.00 | |||
Mammaglobin A Antibody (F-5) PE | sc-515195 PE | 200 µg/ml | $349.00 | |||
Mammaglobin A Antibody (F-5) Alexa Fluor® 488 | sc-515195 AF488 | 200 µg/ml | $364.00 | |||
Mammaglobin A Antibody (F-5) Alexa Fluor® 546 | sc-515195 AF546 | 200 µg/ml | $364.00 | |||
Mammaglobin A Antibody (F-5) Alexa Fluor® 594 | sc-515195 AF594 | 200 µg/ml | $364.00 | |||
Mammaglobin A Antibody (F-5) Alexa Fluor® 647 | sc-515195 AF647 | 200 µg/ml | $364.00 | |||
Mammaglobin A Antibody (F-5) Alexa Fluor® 680 | sc-515195 AF680 | 200 µg/ml | $364.00 | |||
Mammaglobin A Antibody (F-5) Alexa Fluor® 790 | sc-515195 AF790 | 200 µg/ml | $364.00 |