MAGE-D4/MAGE-D4B Antibody (F-3): sc-398908
- MAGE-D4/MAGE-D4B Antibody (F-3) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 62-85 within an internal region of MAGE-D4 of human origin
- recommended for detection of MAGE-D4 and MAGE-D4B of human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for MAGE-D4/MAGE-D4B Antibody (F-3) for WB applications. These reagents are now offered in bundles with MAGE-D4/MAGE-D4B Antibody (F-3) (see ordering information below).
MAGE-D4/MAGE-D4B Antibody (F-3) is a mouse monoclonal IgG2a antibody that detects MAGE-D4/MAGE-D4B in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). MAGE-D4 and MAGE-D4B are 741 amino acid proteins encoded by the human genes MAGED4 and MAGED4B, respectively, and are part of the MAGE family, which directs the expression of tumor antigens recognized by autologous cytolytic T lymphocytes in human melanomas. MAGE-D4 and MAGE-D4B are glioma-specific members of the MAGE family, with expression restricted to glioma cells among cancer types, while normal tissue expression is limited to the brain and ovary. The unique expression pattern of MAGE-D4/MAGE-D4B in gliomas highlights their potential role in tumor immunology, as these proteins may serve as targets for immunotherapeutic strategies. Post-translational modifications can influence MAGE-D4/MAGE-D4B stability and interactions, which is crucial for understanding functional roles in tumor biology. Anti-MAGE-D4/MAGE-D4B antibody (F-3) provides a valuable tool for researchers investigating the molecular mechanisms of glioma and the potential for targeted therapies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MAGE-D4/MAGE-D4B Antibody (F-3) | sc-398908 | 200 µg/ml | $322.00 | |||
MAGE-D4/MAGE-D4B Antibody (F-3): m-IgG Fc BP-HRP Bundle | sc-538543 | 200 µg Ab; 10 µg BP | $361.00 | |||
MAGE-D4/MAGE-D4B Antibody (F-3): m-IgGκ BP-HRP Bundle | sc-536177 | 200 µg Ab; 40 µg BP | $361.00 | |||
MAGE-D4/MAGE-D4B (F-3) Neutralizing Peptide | sc-398908 P | 100 µg/0.5 ml | $69.00 |