MAGE Antibody (F-1): sc-398986
- MAGE Antibody (F-1) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 241-265 near the C-terminus of MAGE-A1 of human origin
- recommended for detection of a broad range of MAGE family members of human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for MAGE Antibody (F-1) for WB applications. These reagents are now offered in bundles with MAGE Antibody (F-1) (see ordering information below).
MAGE Antibody (F-1) is a mouse monoclonal IgG1 antibody that detects MAGE in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-MAGE antibody (F-1) targets the melanoma-associated antigen (MAGE) family, which is crucial for cancer immunotherapy due to tumor-specific expression. MAGE proteins are primarily located in the cytoplasm of tumor cells, where they play a significant role in eliciting immune responses against cancer. Their restricted expression in adult tissues, primarily in tumors and the testis, underscores their potential as biomarkers for cancer diagnosis and targets for therapeutic interventions. The unique expression pattern of MAGE proteins in tumors, coupled with their ability to be recognized by cytotoxic T lymphocytes, highlights their importance in developing effective cancer treatments. Understanding the localization and function of MAGE proteins can provide insights into their role in tumor biology and the immune system′s response to cancer, making MAGE (F-1) antibody an invaluable tool for researchers studying cancer immunology and therapy.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MAGE Antibody (F-1) | sc-398986 | 200 µg/ml | $322.00 | |||
MAGE Antibody (F-1): m-IgG Fc BP-HRP Bundle | sc-538560 | 200 µg Ab; 10 µg BP | $361.00 | |||
MAGE Antibody (F-1): m-IgGκ BP-HRP Bundle | sc-536198 | 200 µg Ab; 40 µg BP | $361.00 | |||
MAGE Antibody (F-1): m-IgG1 BP-HRP Bundle | sc-545767 | 200 µg Ab; 20 µg BP | $361.00 | |||
MAGE (F-1) Neutralizing Peptide | sc-398986 P | 100 µg/0.5 ml | $69.00 |