MAGE Antibody (B-5): sc-365150
- MAGE Antibody (B-5) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 1-309 representing full length MAGE-A1-A1 of human origin
- recommended for detection of all MAGE family members of human origin by WB, IP, IF, IHC(P) and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for MAGE Antibody (B-5) for WB and IHC(P) applications. These reagents are now offered in bundles with MAGE Antibody (B-5) (see ordering information below).
MAGE Antibody (B-5) is a mouse monoclonal IgG1 antibody that detects melanoma-associated antigen (MAGE) in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Anti-MAGE antibody (B-5) targets a member of the MAGE family, which is known for its role in eliciting immune responses against tumors, making MAGE a significant focus in cancer immunotherapy. MAGE proteins are primarily located in the cytoplasm of tumor cells, and MAGE expression is largely restricted to malignant tissues, with notable exceptions in the testis and placenta. This unique expression pattern allows for the development of targeted therapies that can selectively attack cancer cells while sparing normal tissues, thereby minimizing potential side effects. MAGE proteins are also involved in various cellular processes, including apoptosis and cell cycle regulation, which further underscores MAGE importance in tumor biology and the potential for therapeutic intervention. MAGE monoclonal antibody (B-5) enables researchers to gain valuable insights into MAGE protein expression and function in cancer, paving the way for advancements in targeted cancer treatments.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MAGE Antibody (B-5) | sc-365150 | 200 µg/ml | $322.00 | |||
MAGE Antibody (B-5): m-IgG Fc BP-HRP Bundle | sc-537779 | 200 µg Ab; 10 µg BP | $361.00 | |||
MAGE Antibody (B-5): m-IgGκ BP-HRP Bundle | sc-535161 | 200 µg Ab; 40 µg BP | $361.00 | |||
MAGE Antibody (B-5): m-IgG1 BP-HRP Bundle | sc-545346 | 200 µg Ab; 20 µg BP | $361.00 |