LRRC47 Antibody (F-9): sc-398445
- LRRC47 Antibody (F-9) is a mouse monoclonal IgG2b κ LRRC47 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 25-52 near the N-terminus of LRRC47 of human origin
- LRRC47 Antibody (F-9) is recommended for detection of LRRC47 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-LRRC47 Antibody (F-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for LRRC47 Antibody (F-9) for WB applications. These reagents are now offered in bundles with LRRC47 Antibody (F-9) (see ordering information below).
LRRC47 Antibody (F-9) is a mouse monoclonal IgG2b kappa light chain antibody that detects LRRC47 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). LRRC47 (F-9) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. LRRC47 plays a crucial role in immune response, particularly in T cell activation and differentiation regulation, which is vital for maintaining immune homeostasis and preventing autoimmune diseases. By modulating signaling pathways involved in T cell responses, LRRC47 can influence various immune-related conditions, making LRRC47 an important target for therapeutic interventions. Additionally, aberrations in LRRC47 expression have been linked to certain cancers, highlighting LRRC47′s potential as a biomarker for disease progression. Understanding LRRC47 function not only sheds light on immune regulation but also opens avenues for research into targeted therapies that could enhance immune responses in cancer or suppress them in autoimmune disorders.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
LRRC47 Antibody (F-9) References:
- Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family. | Blackwood, DH., et al. 2001. Am J Hum Genet. 69: 428-33. PMID: 11443544
- New insights into the evolution of chromosome 1. | Weise, A., et al. 2005. Cytogenet Genome Res. 108: 217-22. PMID: 15545733
- Hutchinson-Gilford progeria mutant lamin A primarily targets human vascular cells as detected by an anti-Lamin A G608G antibody. | McClintock, D., et al. 2006. Proc Natl Acad Sci U S A. 103: 2154-9. PMID: 16461887
- Cell biology: ageing nucleus gets out of shape. | Lans, H. and Hoeijmakers, JH. 2006. Nature. 440: 32-4. PMID: 16511477
- Chromosome 1 abnormalities in multiple myeloma. | Marzin, Y., et al. 2006. Anticancer Res. 26: 953-9. PMID: 16619492
- Genes and schizophrenia: beyond schizophrenia: the role of DISC1 in major mental illness. | Hennah, W., et al. 2006. Schizophr Bull. 32: 409-16. PMID: 16699061
- The DNA sequence and biological annotation of human chromosome 1. | Gregory, SG., et al. 2006. Nature. 441: 315-21. PMID: 16710414
- Genomic organization of the selectin family of leukocyte adhesion molecules on human and mouse chromosome 1. | Watson, ML., et al. 1990. J Exp Med. 172: 263-72. PMID: 1694218
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
LRRC47 Antibody (F-9) | sc-398445 | 200 µg/ml | $322.00 | |||
LRRC47 Antibody (F-9): m-IgG Fc BP-HRP Bundle | sc-530801 | 200 µg Ab; 10 µg BP | $361.00 | |||
LRRC47 Antibody (F-9): m-IgGκ BP-HRP Bundle | sc-524344 | 200 µg Ab, 40 µg BP | $361.00 | |||
LRRC47 Antibody (F-9): m-IgG2b BP-HRP Bundle | sc-550229 | 200 µg Ab; 10 µg BP | $361.00 | |||
LRRC47 Antibody (F-9) AC | sc-398445 AC | 500 µg/ml, 25% agarose | $424.00 | |||
LRRC47 Antibody (F-9) HRP | sc-398445 HRP | 200 µg/ml | $322.00 | |||
LRRC47 Antibody (F-9) FITC | sc-398445 FITC | 200 µg/ml | $336.00 | |||
LRRC47 Antibody (F-9) PE | sc-398445 PE | 200 µg/ml | $349.00 | |||
LRRC47 Antibody (F-9) Alexa Fluor® 488 | sc-398445 AF488 | 200 µg/ml | $364.00 | |||
LRRC47 Antibody (F-9) Alexa Fluor® 546 | sc-398445 AF546 | 200 µg/ml | $364.00 | |||
LRRC47 Antibody (F-9) Alexa Fluor® 594 | sc-398445 AF594 | 200 µg/ml | $364.00 | |||
LRRC47 Antibody (F-9) Alexa Fluor® 647 | sc-398445 AF647 | 200 µg/ml | $364.00 | |||
LRRC47 Antibody (F-9) Alexa Fluor® 680 | sc-398445 AF680 | 200 µg/ml | $364.00 | |||
LRRC47 Antibody (F-9) Alexa Fluor® 790 | sc-398445 AF790 | 200 µg/ml | $364.00 | |||
LRRC47 (F-9) Neutralizing Peptide | sc-398445 P | 100 µg/0.5 ml | $69.00 |