Liprin α2 Antibody (C-10): sc-393292

Liprin α2 Antibody (C-10) is a mouse monoclonal IgG2a antibody that detects Liprin α2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Liprin α2, also known as PTPRF-interacting protein α2, plays a crucial role in regulating the disassembly of focal adhesions, which are essential for cell migration and signaling. This protein is predominantly expressed in the brain and prostate, where Liprin α2 contributes to various cellular processes, including the maintenance of cell adhesion and communication. Notably, Liprin α2 is downregulated by dihydrotestosterone in prostate cancer cells in an androgen-dependent manner, suggesting that Liprin α2 loss may be linked to the development of androgen-independent characteristics in prostate cancer. The ability of Liprin α2 to interact with members of the leukocyte common antigen-related family of transmembrane protein tyrosine phosphatases further underscores Liprin α2′s importance in cellular signaling pathways, particularly in axon guidance and mammary gland development. Anti-Liprin α2 antibody (C-10) is an invaluable tool for researchers investigating the molecular mechanisms underlying these processes and the implications of Liprin α2 in cancer biology.

The preferred Liprin α2 antibody is Liprin α2 Antibody (H-2): sc-393299.