Liprin α2 Antibody (H-2): sc-393299
- Liprin α2 Antibody (H-2) is a mouse monoclonal IgG1 κ Liprin α2 antibody, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 489-590 mapping within an internal region of Liprin α2 of human origin
- Liprin alpha 2 Antibody (H-2) is recommended for detection of Liprin α2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine and bovine
- Anti-Liprin alpha 2 Antibody (H-2) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Liprin α2 Antibody (H-2) for WB applications. These reagents are now offered in bundles with Liprin α2 Antibody (H-2) (see ordering information below).
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Liprin α2 Antibody (H-2) is a mouse monoclonal IgG1 kappa light chain antibody that detects Liprin alpha 2 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Liprin α2 (H-2) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Liprin alpha 2 protein plays a crucial role in cellular signaling and structural organization, particularly in synapse formation and maintenance in the nervous system. Liprin alpha 2 acts as a scaffold facilitating signaling complex assembly, essential for proper neuronal communication and plasticity. Liprin alpha 2 is involved in focal adhesion disassembly regulation, a process vital for cell migration and tissue remodeling. Liprin alpha 2 is predominantly expressed in brain and prostate, with expression modulated by factors such as dihydrotestosterone in prostate cancer cells, highlighting potential roles in cancer progression. Liprin alpha 2 interaction with leukocyte common antigen-related family of transmembrane protein tyrosine phosphatases underscores importance in various developmental processes, including axon guidance and mammary gland development.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Liprin α2 Antibody (H-2) References:
- The liprin protein SYD-2 regulates the differentiation of presynaptic termini in C. elegans. | Zhen, M. and Jin, Y. 1999. Nature. 401: 371-5. PMID: 10517634
- Drosophila liprin-alpha and the receptor phosphatase Dlar control synapse morphogenesis. | Kaufmann, N., et al. 2002. Neuron. 34: 27-38. PMID: 11931739
- Liprin-alpha2 gene, protein tyrosine phosphatase LAR interacting protein related gene, is downregulated by androgens in the human prostate cancer cell line LNCaP. | Fujinami, K., et al. 2002. Int J Mol Med. 10: 173-6. PMID: 12119554
- Interaction between liprin-alpha and GIT1 is required for AMPA receptor targeting. | Ko, J., et al. 2003. J Neurosci. 23: 1667-77. PMID: 12629171
- Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins. | Ko, J., et al. 2003. J Biol Chem. 278: 42377-85. PMID: 12923177
- Direct observation demonstrates that Liprin-alpha is required for trafficking of synaptic vesicles. | Miller, KE., et al. 2005. Curr Biol. 15: 684-9. PMID: 15823543
- Synaptic transmission regulated by a presynaptic MALS/Liprin-alpha protein complex. | Olsen, O., et al. 2006. Curr Opin Cell Biol. 18: 223-7. PMID: 16504495
- Liprin-alpha has LAR-independent functions in R7 photoreceptor axon targeting. | Hofmeyer, K., et al. 2006. Proc Natl Acad Sci U S A. 103: 11595-600. PMID: 16864797
- Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins. | Serra-Pagès, C., et al. 1998. J Biol Chem. 273: 15611-20. PMID: 9624153
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Liprin α2 Antibody (H-2) | sc-393299 | 200 µg/ml | $316.00 | |||
Liprin α2 Antibody (H-2): m-IgG Fc BP-HRP Bundle | sc-527678 | 200 µg Ab; 10 µg BP | $354.00 | |||
Liprin α2 Antibody (H-2): m-IgG1 BP-HRP Bundle | sc-533051 | 200 µg Ab; 20 µg BP | $354.00 | |||
Liprin α2 Antibody (H-2) AC | sc-393299 AC | 500 µg/ml, 25% agarose | $416.00 | |||
Liprin α2 Antibody (H-2) HRP | sc-393299 HRP | 200 µg/ml | $316.00 | |||
Liprin α2 Antibody (H-2) FITC | sc-393299 FITC | 200 µg/ml | $330.00 | |||
Liprin α2 Antibody (H-2) PE | sc-393299 PE | 200 µg/ml | $343.00 | |||
Liprin α2 Antibody (H-2) Alexa Fluor® 488 | sc-393299 AF488 | 200 µg/ml | $357.00 | |||
Liprin α2 Antibody (H-2) Alexa Fluor® 546 | sc-393299 AF546 | 200 µg/ml | $357.00 | |||
Liprin α2 Antibody (H-2) Alexa Fluor® 594 | sc-393299 AF594 | 200 µg/ml | $357.00 | |||
Liprin α2 Antibody (H-2) Alexa Fluor® 647 | sc-393299 AF647 | 200 µg/ml | $357.00 | |||
Liprin α2 Antibody (H-2) Alexa Fluor® 680 | sc-393299 AF680 | 200 µg/ml | $357.00 | |||
Liprin α2 Antibody (H-2) Alexa Fluor® 790 | sc-393299 AF790 | 200 µg/ml | $357.00 |