Lamin A/C Antibody (4C11): sc-517579

Lamin A/C Antibody (4C11) is a mouse monoclonal IgG2a antibody that detects Lamin A/C in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Lamin A/C plays a crucial role in maintaining the structural integrity of the nuclear envelope, which is essential for proper cellular function and organization. Anti-Lamin A/C antibody (4C11) targets proteins located in the nuclear lamina, a dense fibrillar network inside the nucleus, where Lamin A/C provides mechanical support and regulates important processes such as DNA replication and cell division. Lamin A/C monoclonal antibody (4C11) enables research beyond structural support, as Lamin A/C is involved in chromatin organization and gene expression regulation. Notably, mutations in the Lamin A gene can lead to a variety of diseases, including muscular dystrophies and progeria, highlighting the importance of Lamin A/C in cellular health and longevity. Lamin A/C (4C11) antibody serves as an invaluable tool for researchers studying the dynamics of the nuclear envelope and its implications in various pathologies, enabling deeper insights into the molecular mechanisms underlying cellular aging and disease progression.

The preferred Lamin A/C antibody is Lamin A/C Antibody (636): sc-7292.