Lambda 5 Antibody (G-12): sc-398037
- Lambda 5 Antibody (G-12) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 31-56 at the N-terminus of Lambda 5 of mouse origin
- recommended for detection of Lambda 5 of mouse and rat origin by WB, IP, IF and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Lambda 5 Antibody (G-12). This work is in progress.
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Lambda 5 Antibody (G-12) is a mouse monoclonal IgG1 antibody that detects Lambda 5 in mouse and rat samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Lambda 5, also known as Immunoglobulin lambda-like polypeptide 1 or CD179b antigen, plays a pivotal role in B cell development by forming part of the surrogate light chain of the pre-B cell receptor complex alongside VpreB. Lambda 5 (G-12) antibody helps identify this complex, which is essential for the quality control mechanism that ensures successful pairing of the heavy chain with conventional light chains, crucial for functional antibody formation. Lambda 5 expression is predominantly observed in the liver, pre-B lymphocytes, and bone marrow, which are key sites for B cell precursor development. Lambda 5 expression begins in pro-B cells, continues through the pre-B cell stage, and decreases upon transition to immature B cells. This regulation prevents excessive pre-B cell receptor formation, maintaining the balance necessary for effective B cell maturation and function. Lambda 5 (G-12) monoclonal antibody serves as an invaluable tool for researchers studying B cell biology and immune response mechanisms.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Lambda 5 Antibody (G-12) | sc-398037 | 200 µg/ml | $316.00 | |||
Lambda 5 (G-12) Neutralizing Peptide | sc-398037 P | 100 µg/0.5 ml | $68.00 |