ISG15 Antibody (E-9): sc-166794
- ISG15 Antibody (E-9) is a mouse monoclonal IgG2a κ, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 1-150 mapping at the N-terminus of ISG15 of mouse origin
- recommended for detection of ISG15 of mouse origin by WB, IP, IF and ELISA
- See ISG15 (F-9): sc-166755 for ISG15 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ISG15 Antibody (E-9) for WB applications. These reagents are now offered in bundles with ISG15 Antibody (E-9) (see ordering information below).
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ISG15 Antibody (E-9) is a mouse monoclonal IgG2a antibody that detects ISG15 in mouse samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-ISG15 antibody (E-9) is raised against amino acids 1-150 mapping at the N-terminus of ISG15 of mouse origin. ISG15, a 15 kDa protein, plays a crucial role in the immune response by functioning as a ubiquitin-like modifier, conjugating to various intracellular target proteins, including JAK1 and MAPK3/ERK1, through a unique enzymatic pathway that is distinct from that of ubiquitin. This modification is vital for regulating protein stability and activity, thereby influencing key signaling pathways involved in immune responses. Additionally, ISG15 (E-9) monoclonal antibody exhibits specific chemotactic activity towards neutrophils, activating them to release eosinophil chemotactic factors, which further underscores ISG15′s importance in orchestrating immune cell interactions. ISG15 is predominantly located in the cytoplasm and is expressed in muscle, epithelial, neuronal, and lymphoid cells, highlighting ISG15′s diverse roles in various tissues. ISG15 monoclonal antibody (E-9) undergoes conjugation to target proteins through a process known as ISGylation, a post-translational modification that enhances protein stability, regulates immune signaling pathways, and modulates antiviral responses, making ISG15 critical for maintaining cellular homeostasis during infection. Anti-ISG15 antibody (E-9) is an essential tool for researchers studying the intricate mechanisms of immune modulation and cellular signaling in mouse models.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ISG15 Antibody (E-9) | sc-166794 | 200 µg/ml | $322.00 | |||
ISG15 Antibody (E-9): m-IgG Fc BP-HRP Bundle | sc-537532 | 200 µg Ab; 10 µg BP | $361.00 | |||
ISG15 Antibody (E-9): m-IgGκ BP-HRP Bundle | sc-534825 | 200 µg Ab; 40 µg BP | $361.00 | |||
ISG15 Antibody (E-9): m-IgG2a BP-HRP Bundle | sc-548046 | 200 µg Ab; 10 µg BP | $361.00 |