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Integrin αIIb/ITGA2B/CD41 Antibody (A-7): sc-373992

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Datasheets
  • Integrin αIIb/ITGA2B/CD41 Antibody (A-7) is a mouse monoclonal IgG3 κ provided at 200 µg/ml
  • raised against amino acids 847-1006 mapping near the C-terminus of Integrin αIIb of human origin
  • recommended for detection of Integrin αIIb heavy and light chain of mouse, rat and human origin by WB, IP, IF and ELISA
  • See Integrin αIIb/ITGA2B/CD41 (B-9): sc-365938 for Integrin αIIb/ITGA2B/CD41 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • m-IgG3 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Integrin αIIb/ITGA2B/CD41 Antibody (A-7) for WB applications. These reagents are now offered in bundles with Integrin αIIb/ITGA2B/CD41 Antibody (A-7) (see ordering information below).

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    Integrin αIIb Antibody (A-7) is a mouse monoclonal IgG3 antibody that detects Integrin αIIb in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Integrin αIIb is a crucial component of the integrin family, primarily expressed on platelets, where anti-Integrin αIIb antibody (A-7) plays a vital role in hemostasis and thrombosis by mediating platelet aggregation. Integrin αIIb forms a heterodimer with the β3 subunit, resulting in the integrin αIIbβ3 complex, which binds to fibrinogen and other extracellular matrix proteins, facilitating the adhesion and aggregation of platelets at sites of vascular injury. Proper functioning of Integrin αIIb is essential for normal blood clotting processes, and dysregulation can lead to bleeding disorders or thrombotic diseases. Integrin αIIb monoclonal antibody (A-7) provides reliable detection and characterization, enabling researchers to explore its role in various physiological and pathological conditions.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    Integrin αIIb/ITGA2B/CD41 Antibody (A-7)

    sc-373992
    200 µg/ml
    $316.00

    Integrin αIIb/ITGA2B/CD41 Antibody (A-7): m-IgGκ BP-HRP Bundle

    sc-535360
    200 µg Ab; 40 µg BP
    $354.00

    Integrin αIIb/ITGA2B/CD41 Antibody (A-7): m-IgG3 BP-HRP Bundle

    sc-550307
    200 µg Ab; 40 µg BP
    $354.00

    Integrin αIIb/ITGA2B/CD41 (A-7) Neutralizing Peptide

    sc-373992 P
    100 µg/0.5 ml
    $68.00

    What application is the blocking peptide sc-373992 P appropriate for?

    Asked by: Professor Griffin
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-02-27
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    Rated 4 out of 5 by from ntegrin IIb detected by western blot in HEL 92ntegrin IIb detected by western blot in HEL 92.1.7 whole cell lysate. -SCBT QC
    Date published: 2014-05-08
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    Integrin αIIb/ITGA2B/CD41 Antibody (A-7) is rated 4.0 out of 5 by 1.
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