IL-21R Antibody (G-6): sc-515062

IL-21R Antibody (G-6) is a mouse monoclonal IgG2a antibody that detects IL-21R in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). IL-21R, also known as the interleukin-21 receptor, plays a crucial role in the immune system by mediating the effects of IL-21, a cytokine that influences lymphocyte proliferation and differentiation. IL-21R is predominantly located on the surface of natural killer cells, B cells, and T cells, with particularly high expression levels in the spleen and thymus, which are vital sites for immune cell development and function. IL-21R in these locations underscores its importance in bridging innate and adaptive immunity, facilitating the transition and coordination between these two arms of the immune response. Additionally, the IL-21R gene, located on chromosome 16p11, encodes a 538 amino acid protein that shares significant sequence identity with the mouse IL-21R, highlighting its evolutionary conservation and functional relevance across species. Anti-IL-21R antibody (G-6) is an essential tool for researchers studying immune responses, lymphoid development, and potential therapeutic targets in various diseases, including cancers and autoimmune disorders.

The preferred IL-21R antibody is IL-21R Antibody (H-11): sc-137120.