Date published: 2025-12-18

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IL-21R Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of IL-21R monoclonal antibodies for research focused on understanding the role of the IL-21 receptor in immune responses. IL-21R Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). The IL-21 receptor mediates the effects of interleukin-21, a cytokine involved in the regulation of immune cell functions, including the differentiation of T and B cells. Research has shown IL-21R plays a significant role in autoimmune diseases, infections, and cancer development. Investigating IL-21R signaling pathways and molecular interactions helps advance understanding of immune system regulation. Scientists studying IL-21R can uncover new therapeutic approaches for immune-related conditions. Current research highlights the importance of IL-21R in both normal immune function and disease states. Exploring IL-21R mechanisms continues to reveal promising directions for immunotherapy development. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of immune system regulation and potential therapeutic applications.

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IL-21R Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

IL-21R Antibody (H-11)

sc-137120mouse IgG3 κ473-509 (h)WB, IP, IF, ELISAm, r, h
2
(2)

IL-21R Antibody (G-6)

sc-515062mouse IgG2a κ34-58 (h)WB, IP, IF, ELISAh

new

(0)

IL-21R CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IL-21R CRISPR/Cas9 KO Plasmid (h)

sc-404225hGene KnockoutGFP0
(0)

IL-21R HDR Plasmid (h)

sc-404225-HDRhHomology Directed RepairPuromycin0
(0)

IL-21R Double Nickase Plasmid (h)

sc-404225-NIChGene KnockoutPuromycin0
(0)

IL-21R Double Nickase Plasmid (h2)

sc-404225-NIC-2hGene KnockoutPuromycin0
(0)

IL-21R CRISPR/Cas9 KO Plasmid (m)

sc-425627mGene KnockoutGFP0
(0)

IL-21R HDR Plasmid (m)

sc-425627-HDRmHomology Directed RepairPuromycin0
(0)

IL-21R Double Nickase Plasmid (m)

sc-425627-NICmGene KnockoutPuromycin0
(0)

IL-21R Double Nickase Plasmid (m2)

sc-425627-NIC-2mGene KnockoutPuromycin0
(0)

IL-21R CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IL-21R CRISPR Activation Plasmid (h)

sc-404225-ACThGene ActivationPuro, Blast, Hygro0
(0)

IL-21R CRISPR Activation Plasmid (h2)

sc-404225-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

IL-21R Lentiviral Activation Particles (h)

sc-404225-LAChGene ActivationPuro, Blast, Hygro0
(0)

IL-21R Lentiviral Activation Particles (h2)

sc-404225-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

IL-21R CRISPR Activation Plasmid (m)

sc-425627-ACTmGene ActivationPuro, Blast, Hygro0
(0)

IL-21R CRISPR Activation Plasmid (m2)

sc-425627-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

IL-21R Lentiviral Activation Particles (m)

sc-425627-LACmGene ActivationPuro, Blast, Hygro0
(0)

IL-21R Lentiviral Activation Particles (m2)

sc-425627-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

IL-21R siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IL-21R siRNA (h)

sc-40053hGene SilencingN/A0
(0)

IL-21R shRNA Plasmid (h)

sc-40053-SHhGene SilencingPuromycin0
(0)

IL-21R shRNA (h) Lentiviral Particles

sc-40053-VhGene SilencingPuromycin0
(0)

IL-21R siRNA (m)

sc-40054mGene SilencingN/A0
(0)

IL-21R shRNA Plasmid (m)

sc-40054-SHmGene SilencingPuromycin0
(0)

IL-21R shRNA (m) Lentiviral Particles

sc-40054-VmGene SilencingPuromycin0
(0)