IL-17 Antibody (1): sc-53937

IL-17 Antibody (1) is a mouse monoclonal IgG2b kappa light chain antibody raised against full-length human interleukin-17 (IL-17), also known as IL-17A or CTLA8. IL-17 is a pro-inflammatory cytokine predominantly produced by activated T helper 17 (Th17) cells and plays a crucial role in immune regulation and inflammatory responses. IL-17 is a secreted protein located in the extracellular space, which is essential for its function as IL-17 interacts with its receptor, IL-17R, on various target cells to initiate signal transduction cascades. This extracellular localization facilitates the mediation of communication between immune cells and contributes to the coordination of defense mechanisms against pathogens. Dysregulation of IL-17 expression is associated with autoimmune and inflammatory diseases such as psoriasis, rheumatoid arthritis, and multiple sclerosis. Anti-IL-17 antibody (1) specifically reacts with human IL-17 in western blotting (WB) and enzyme-linked immunosorbent assay (ELISA) applications, making anti-IL-17 antibody (1) a valuable tool for researchers studying IL-17′s role in human immune responses and disease pathogenesis. Anti-IL-17 antibody (1) aids in the exploration of therapeutic strategies aimed at modulating inflammatory processes and developing treatments for autoimmune conditions.

The preferred IL-17 antibody is IL-17 Antibody (G-4): sc-374218.