IARS2 Antibody (B-1): sc-393654

IARS2 Antibody (B-1) is a mouse monoclonal IgG3 antibody that detects IARS2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). IARS2, or Isoleucyl-tRNA synthetase, is a crucial enzyme that plays a vital role in protein synthesis by catalyzing the attachment of isoleucine to its corresponding tRNA, ensuring the accurate translation of genetic information into functional proteins. This process is essential for cellular function and growth, as any errors in amino acid incorporation can lead to dysfunctional proteins and various diseases. IARS2 is localized within the mitochondrial matrix, where IARS2 contributes to mitochondrial protein synthesis, a critical aspect of cellular energy production and metabolism. IARS2 consists of 1,012 amino acids and belongs to the class I mitochondrial aminoacyl-tRNA synthetase family, characterized by a distinctive Rossman fold that facilitates nucleotide binding. The gene encoding IARS2 is located on human chromosome one, the largest chromosome in the human genome, which underscores its significance in maintaining cellular homeostasis and function. Anti-IARS2 antibody (B-1) is an invaluable tool for researchers studying mitochondrial function, protein synthesis, and related pathologies.

The preferred IARS2 antibody is IARS2 Antibody (E-2): sc-393641.