Date published: 2026-1-9

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IARS2 Antibodies

Santa Cruz Biotechnology delivers a wide array of IARS2 monoclonal antibodies for research focused on understanding mitochondrial isoleucyl-tRNA synthetase 2 (IARS2). IARS2 Antibodies targeting IARS2 are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). IARS2 plays a fundamental role in mitochondrial protein synthesis and is essential for maintaining proper mitochondrial function. The protein facilitates the translation of mitochondrial mRNA, which drives the production of key components in the electron transport chain and ATP generation. Mutations in IARS2 have been linked to various mitochondrial diseases and metabolic disorders, making it a significant target for scientific investigation. Research into IARS2 continues to reveal new insights about mitochondrial biology and its impact on cellular health. Understanding IARS2 function helps illuminate the mechanisms behind mitochondrial diseases and potential therapeutic approaches. Investigating IARS2 expression and activity patterns provides valuable information about cellular energy metabolism and protein synthesis pathways. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of mitochondrial biology and its implications for human health.

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IARS2 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

IARS2 Antibody (E-2)

sc-393641mouse IgG1 κ253-272 (h)WB, IP, IF, ELISAm, r, h

new

(2)

IARS2 Antibody (B-1)

sc-393654mouse IgG3 κ249-272 (h)WB, IP, IF, ELISAm, r, h

new

(1)

IARS2 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IARS2 CRISPR/Cas9 KO Plasmid (h)

sc-410022hGene KnockoutGFP0
(0)

IARS2 HDR Plasmid (h)

sc-410022-HDRhHomology Directed RepairPuromycin0
(0)

IARS2 Double Nickase Plasmid (h)

sc-410022-NIChGene KnockoutPuromycin0
(0)

IARS2 Double Nickase Plasmid (h2)

sc-410022-NIC-2hGene KnockoutPuromycin0
(0)

IARS2 CRISPR/Cas9 KO Plasmid (m)

sc-436267mGene KnockoutGFP0
(0)

IARS2 HDR Plasmid (m)

sc-436267-HDRmHomology Directed RepairPuromycin0
(0)

IARS2 Double Nickase Plasmid (m)

sc-436267-NICmGene KnockoutPuromycin0
(0)

IARS2 Double Nickase Plasmid (m2)

sc-436267-NIC-2mGene KnockoutPuromycin0
(0)

IARS2 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IARS2 CRISPR Activation Plasmid (h)

sc-410022-ACThGene ActivationPuro, Blast, Hygro0
(0)

IARS2 CRISPR Activation Plasmid (h2)

sc-410022-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

IARS2 Lentiviral Activation Particles (h)

sc-410022-LAChGene ActivationPuro, Blast, Hygro0
(0)

IARS2 Lentiviral Activation Particles (h2)

sc-410022-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

IARS2 CRISPR Activation Plasmid (m)

sc-436267-ACTmGene ActivationPuro, Blast, Hygro0
(0)

IARS2 CRISPR Activation Plasmid (m2)

sc-436267-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

IARS2 Lentiviral Activation Particles (m)

sc-436267-LACmGene ActivationPuro, Blast, Hygro0
(0)

IARS2 Lentiviral Activation Particles (m2)

sc-436267-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

IARS2 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IARS2 siRNA (h)

sc-88313hGene SilencingN/A0
(0)

IARS2 shRNA Plasmid (h)

sc-88313-SHhGene SilencingPuromycin0
(0)

IARS2 shRNA (h) Lentiviral Particles

sc-88313-VhGene SilencingPuromycin0
(0)

IARS2 siRNA (m)

sc-146128mGene SilencingN/A0
(0)

IARS2 shRNA Plasmid (m)

sc-146128-SHmGene SilencingPuromycin0
(0)

IARS2 shRNA (m) Lentiviral Particles

sc-146128-VmGene SilencingPuromycin0
(0)