HSP 27 Antibody (G3.1): sc-59562
- HSP 27 Antibody (G3.1) is a mouse monoclonal IgG1, cited in 7 publications, provided at 100 µg/ml
- raised against partially purified HSP 27 derived from MCF-7 cytosol of human origin
- recommended for detection of HSP 27 of mouse, rat and human origin by WB, IP, IF and IHC(P)
- See HSP 27 (F-4): sc-13132 for HSP 27 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for HSP 27 Antibody (G3.1). This work is in progress.
HSP 27 Antibody (G3.1) is a mouse monoclonal IgG1 antibody that detects HSP 27 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. HSP 27 is a crucial member of the heat shock protein family, functioning primarily as a molecular chaperone that assists in protein folding and protects cells from stress-induced damage. HSP 27 is predominantly located in the cytoplasm but translocates to the nucleus under stress conditions, highlighting its role in cellular response mechanisms. HSP 27′s ability to relocate allows for the regulation of various cellular processes, including apoptosis and cell survival, particularly in response to heat shock, cytokines, and hormonal signals. Notably, HSP 27 undergoes extensive post-translational modifications, including phosphorylation, which enhances chaperone activity and is critical for protective functions during cellular stress. HSP 27′s regulation by hormones like estrogen suggests a potential link to tumorigenesis in breast cancer, making HSP 27 a valuable target for understanding cancer biology and developing therapeutic strategies. Anti-HSP 27 antibody (G3.1) is an essential tool for researchers investigating this protein′s role in various physiological and pathological contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HSP 27 Antibody (G3.1) | sc-59562 | 100 µg/ml | $322.00 |