HoxD9 Antibody (B-9): sc-365717
- HoxD9 Antibody (B-9) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 14-37 at the N-terminus of HoxD9 of human origin
- recommended for detection of HoxD9 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including porcine
- TransCruz reagent for ChIP application (sc-365717 X, 200 µg/0.1 ml)
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for HoxD9 Antibody (B-9) for WB applications. These reagents are now offered in bundles with HoxD9 Antibody (B-9) (see ordering information below).
HoxD9 Antibody (B-9) is a mouse monoclonal IgG2b antibody that detects HoxD9 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). HoxD9 is a critical transcription factor involved in the regulation of embryonic development and cellular differentiation, primarily by modulating downstream target genes. HoxD9′s role is particularly significant in the early stages of joint development, where expression occurs in articular cartilage, indicating importance in skeletal patterning. HoxD9 interacts with the human control region of the HoxD9 gene, facilitating transcriptional activation, which is essential for proper gene expression during development. HoxD9 has been implicated in the pathology of arthritis, as transcripts are found in the synovial tissue of arthritic mice, but absent in normal mice, suggesting a potential role in inflammatory processes. In patients with rheumatoid arthritis, HoxD9 is highly expressed in synoviocytes, contrasting with lack of expression in osteoarthritis cases, highlighting specificity in disease contexts. HoxD9′s differential expression in the cervical cancer cell line HeLa, compared to normal cervical tissue, suggests involvement in tumorigenesis, making anti-HoxD9 antibody (B-9) an invaluable tool for researchers investigating these critical biological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HoxD9 Antibody (B-9) | sc-365717 | 200 µg/ml | $322.00 | |||
HoxD9 Antibody (B-9): m-IgGκ BP-HRP Bundle | sc-535245 | 200 µg Ab; 40 µg BP | $361.00 | |||
HoxD9 Antibody (B-9): m-IgG2b BP-HRP Bundle | sc-549376 | 200 µg Ab; 10 µg BP | $361.00 | |||
HoxD9 (B-9) Neutralizing Peptide | sc-365717 P | 100 µg/0.5 ml | $69.00 | |||
HoxD9 Antibody (B-9) X | sc-365717 X | 200 µg/0.1 ml | $322.00 |