hnRNP A1 Antibody (9H10): sc-56700

hnRNP A1 Antibody (9H10) is a mouse monoclonal IgG2b kappa light chain antibody that detects hnRNP A1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-hnRNP A1 antibody (9H10) is available in a non-conjugated form, allowing for versatile experimental use. hnRNP A1, a member of the heterogeneous nuclear ribonucleoprotein (hnRNP) family, plays a crucial role in mRNA metabolism, including transcription, pre-mRNA processing, and mature mRNA transport to the cytoplasm for translation. hnRNP A1 is primarily located in the nucleus, where hnRNP A1 interacts with heterogeneous nuclear RNA (hnRNA) produced by RNA polymerase II, and is essential for forming spliceosomal complexes that facilitate mRNA splicing. hnRNP A1′s ability to shuttle between the nucleus and cytoplasm enables regulation of gene expression in response to cellular signals. hnRNP A1 interacts with various splicing factors, influencing splice site selection and impacting the diversity of mRNA isoforms produced from a single gene. Understanding hnRNP A1′s function and dynamics is vital for elucidating gene regulation complexities and molecular mechanisms underlying various diseases, including cancer and neurodegenerative disorders.

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-hnRNP A1 Antibody (9H10) has 17 citations in a variety of scientific publications.

Primary antibodies like Anti-hnRNP A1 Antibody (9H10) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

hnRNP A1 Antibody (9H10) Specifications

Alternate Product Name: hnRNP A1

Product Clone Name: 9H10

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2b kappa light chain

Amino Acids:

Epitope Target: hnRNP A1

Epitope Species: human

Product Reactivity/Detection: hnRNP A1

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG_2b kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 17 citations in various scientific publications

Available Conjugates/Forms for hnRNP A1 Antibody (9H10): N/A

The preferred hnRNP A1 antibody is hnRNP A1 Antibody (4B10): sc-32301.