HLA-DR Antibody (Bra30): sc-33717

HLA-DR Antibody (Bra30) is a mouse monoclonal IgG2a kappa light chain antibody designed to target the HLA-DR protein, also known as human leukocyte antigen DR or MHC class II DR. HLA-DR protein is primarily located on the surface of antigen-presenting cells such as B lymphocytes, dendritic cells, and macrophages, where HLA-DR plays a crucial role in the immune system by presenting antigenic peptides to CD4+ T helper cells. This interaction is essential for initiating and regulating immune responses, making HLA-DR a key player in pathogen defense and immune surveillance. Anti-HLA-DR antibody (Bra30) is raised against the Reh-6 non-T, non-B leukemia cell line and exhibits strong reactivity with HLA-DR from mouse, rat, and human species, making anti-HLA-DR antibody (Bra30) versatile for use in western blotting (WB), immunoprecipitation (IP), and flow cytometry (FCM) applications. HLA-DR monoclonal antibody (Bra30) specificity for HLA-DR ensures no cross-reactivity with other MHC class II molecules, providing reliable and precise detection in various experimental settings. Available in both conjugated and unconjugated forms, HLA-DR (Bra30) antibody is an indispensable tool for researchers investigating antigen presentation mechanisms, immune cell interactions, and the molecular basis of immune-related diseases such as autoimmune disorders and cancers. By facilitating the detailed study of HLA-DR localization and function within cells, anti-HLA-DR antibody (Bra30) supports the advancement of targeted immunotherapies and the development of novel diagnostic strategies, ultimately contributing to improved patient outcomes and a deeper understanding of immune regulation.

The preferred HLA-DR antibody is HLA-DR Antibody (L243): sc-18875.