HLA-DR Antibody (520B): sc-69673
- HLA-DR Antibody (520B) is a mouse monoclonal IgG2b κ HLA-DR antibody, cited in 2 publications, provided at 200 µg/ml
- raised against lymphoma cells of human origin
- HLA-DR Antibody (520B) is recommended for detection of HLA-DR of human origin by WB, IP, IF, IHC(P) and FCM
- Anti-HLA-DR Antibody (520B) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG2b BP-HRP are the preferred secondary detection reagents for HLA-DR Antibody (520B) for WB and IHC(P) applications. These reagents are now offered in bundles with HLA-DR Antibody (520B) (see ordering information below).
HLA-DR Antibody (520B) is a mouse monoclonal IgG2b kappa light chain antibody, designed to target the HLA-DR protein, also known as Human Leukocyte Antigen-DR or Major Histocompatibility Complex (MHC) class II DR isotype. Anti-HLA-DR antibody (520B) is raised against lymphoma cells of human origin and demonstrates strong reactivity with HLA-DR proteins from human species, making anti-HLA-DR antibody (520B) ideal for applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). The HLA-DR protein is a crucial component of the immune system, functioning as an α/β heterodimer that presents exogenous peptides to CD4+ helper T cells, thereby initiating and regulating immune responses. Structurally, HLA-DR undergoes important post-translational modifications, including glycosylation, which are essential for proper folding, stability, and interaction with peptide antigens and T cell receptors. These modifications ensure accurate presentation of antigens and play a significant role in immune system functionality and disease susceptibility. Additionally, HLA-DR is involved in various autoimmune conditions, with certain polymorphisms linked to increased risk of diseases such as rheumatoid arthritis. HLA-DR monoclonal antibody (520B) is available in both non-conjugated and multiple conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and various Alexa Fluor® conjugates, providing versatile options for diverse experimental needs. By targeting the HLA-DR protein, anti-HLA-DR antibody (520B) facilitates advanced research into immune mechanisms, autoimmune disease pathways, and development of therapeutic interventions. The robust specificity and reliable performance of HLA-DR monoclonal antibody (520B) make anti-HLA-DR antibody (520B) an indispensable tool for researchers exploring the complexities of the immune system.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HLA-DR Antibody (520B) | sc-69673 | 200 µg/ml | $322.00 | |||
HLA-DR Antibody (520B): m-IgG Fc BP-HRP Bundle | sc-525690 | 200 µg Ab; 10 µg BP | $361.00 | |||
HLA-DR Antibody (520B): m-IgG2b BP-HRP Bundle | sc-549619 | 200 µg Ab; 10 µg BP | $361.00 | |||
HLA-DR Antibody (520B) AC | sc-69673 AC | 500 µg/ml, 25% agarose | $424.00 | |||
HLA-DR Antibody (520B) HRP | sc-69673 HRP | 200 µg/ml | $322.00 | |||
HLA-DR Antibody (520B) FITC | sc-69673 FITC | 200 µg/ml | $336.00 | |||
HLA-DR Antibody (520B) PE | sc-69673 PE | 200 µg/ml | $349.00 | |||
HLA-DR Antibody (520B) Alexa Fluor® 488 | sc-69673 AF488 | 200 µg/ml | $364.00 | |||
HLA-DR Antibody (520B) Alexa Fluor® 546 | sc-69673 AF546 | 200 µg/ml | $364.00 | |||
HLA-DR Antibody (520B) Alexa Fluor® 594 | sc-69673 AF594 | 200 µg/ml | $364.00 | |||
HLA-DR Antibody (520B) Alexa Fluor® 647 | sc-69673 AF647 | 200 µg/ml | $364.00 | |||
HLA-DR Antibody (520B) Alexa Fluor® 680 | sc-69673 AF680 | 200 µg/ml | $364.00 | |||
HLA-DR Antibody (520B) Alexa Fluor® 790 | sc-69673 AF790 | 200 µg/ml | $364.00 |