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HIV-1 Rev Antibody (Rev-6) is a mouse monoclonal IgG1 antibody that specifically detects HIV-1 Rev in HIV-1 through western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). HIV-1 Rev is a crucial RNA-binding trans-activator protein that facilitates the export of unspliced and partially spliced viral mRNAs from the nucleus to the cytoplasm for viral protein translation. Anti-HIV-1 Rev antibody (Rev-6) enables detection of this essential process for viral replication, which ensures necessary components for new virion assembly are available in the cytoplasm. Phosphorylation of HIV-1 Rev by protein kinase CK2 and MAP kinase at distinct regions enhances activity and stability, highlighting the importance of post-translational modifications in regulating function. HIV-1 Rev monoclonal antibody (Rev-6) helps researchers understand HIV-1 replication mechanisms and Rev′s role in the viral life cycle, advancing development of targeted therapies against HIV/AIDS.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HIV-1 Rev Antibody (Rev-6) | sc-69730 | 200 µg/ml | $316.00 | |||
HIV-1 Rev Antibody (Rev-6): m-IgG Fc BP-HRP Bundle | sc-539232 | 200 µg Ab; 10 µg BP | $354.00 | |||
HIV-1 Rev Antibody (Rev-6): m-IgG1 BP-HRP Bundle | sc-541341 | 200 µg Ab; 20 µg BP | $354.00 |