HIV-1 Nef Antibodies

Santa Cruz Biotechnology provides a broad selection of HIV-1 Nef monoclonal antibodies for research focused on understanding the complex interactions of the HIV-1 virus. HIV-1 Nef Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA).HIV-1 Nef is a critical accessory protein that plays a significant role in the pathogenesis of HIV-1 by modulating the immune response and enhancing viral replication. HIV-1 Nef downregulates CD4 and major histocompatibility complex (MHC) class I molecules, which helps the virus evade the host immune system. Understanding HIV-1 Nef function is essential for developing therapeutic strategies and vaccines against HIV. Research has shown that HIV-1 Nef influences cellular signaling pathways and protein trafficking within infected cells. HIV-1 Nef also impacts T-cell activation and cellular metabolism during infection. Recent studies have revealed new aspects of HIV-1 Nef's role in viral spread and immune evasion. Santa Cruz Biotechnology monoclonal antibodies enable researchers to advance HIV research and contribute to developing new therapeutic approaches for HIV treatment.