Date published: 2026-4-5

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Histone H1 Antibody (G-1): sc-393530

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Datasheets
  • Histone H1 Antibody (G-1) is a mouse monoclonal IgM κ, cited in 4 publications, provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 196-219 at the C-terminus of Histone H1 of human origin
  • recommended for detection of all histone H1 isoforms of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
  • See Histone H1 (H-2): sc-393358 for Histone H1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Histone H1 Antibody (G-1). This work is in progress.
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Histone H1 Antibody (G-1) is a mouse monoclonal IgM antibody that detects Histone H1 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Histone H1 plays a crucial role in the structural organization of chromatin, acting as a linker histone that binds to the nucleosome and facilitates the compaction of DNA into higher-order structures. This compaction is essential for the regulation of gene expression and DNA replication, as Histone H1 influences the accessibility of transcription factors and other regulatory proteins to the DNA. Histone H1 maintains chromatin integrity during cell division and ensures proper genomic stability. Additionally, Histone H1 undergoes various post-translational modifications, such as phosphorylation and acetylation, which can further modulate function and interactions with other chromatin-associated proteins. Anti-Histone H1 antibody (G-1) enables researchers to gain insights into the dynamic processes of chromatin remodeling and gene regulation, contributing to a deeper understanding of cellular functions and disease mechanisms.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Histone H1 Antibody (G-1)

sc-393530
200 µg/ml
$322.00

Histone H1 (G-1) Neutralizing Peptide

sc-393530 P
100 µg/0.5 ml
$69.00

We need a primary antibody that recognizes the somatic form of the linker histone H1 in pig cells by IF. Which of your antibodies would you recommend? Would it be possible to send me a small aliquot test it in pig cells before we order it?

Asked by: Vilceu
Thank you for your question. I would suggest using sc-8030 for your purpose. Unfortunately we do not have a sample of this particular antibody clone, but we do have samples of another one that would be a good choice, sc-56695. If you would like to try a sample, please contact Technical Service by phone, (800)-457-3801 option 2, email <scbt@scbt.com>, or by live chat directly on our website, www.scbt.com.
Answered by: Tech Service
Date published: 2017-07-05

What application is the blocking peptide sc-393530 P appropriate for?

Asked by: AbPolly
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
  • y_2026, m_3, d_27, h_8CST
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Rated 5 out of 5 by from 使いやすいH2やH3関連のWBを行うことが多く、コントロールとしてH1は用いやすいです。バンドもしっかり出ました。
Date published: 2024-04-25
Rated 5 out of 5 by from Works well for IF applicationsWorks well for IF applications, nuclear staining in MeOH fixed HeLa cells. -SCBT QC
Date published: 2015-04-08
Rated 5 out of 5 by from Great antibody for WesternGreat antibody for Western, strong Histone H1 band detected in Jurkat nuclear extract and LNCaP whole cell lysate. -SCBT QC
Date published: 2014-04-21
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Histone H1 Antibody (G-1) is rated 5.0 out of 5 by 3.
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