Histone Deacetylase 2 (HDAC2) Antibody (3F3): sc-81599

HDAC2 Antibody (3F3) is a mouse monoclonal IgG1 kappa light chain antibody that detects Histone Deacetylase 2 (HDAC2) in mouse, rat, human, and bovine samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Anti-HDAC2 antibody (3F3) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. HDAC2 plays a crucial role in the regulation of gene expression by removing acetyl groups from histones, leading to chromatin condensation and transcriptional repression. This deacetylation process is vital for maintaining cellular homeostasis and regulating various biological processes, including cell cycle progression, differentiation, and apoptosis. Dysregulation of HDAC2 has been implicated in several diseases, including cancer, where aberrant histone deacetylation can lead to the silencing of tumor suppressor genes. Understanding HDAC2 function and interactions with other proteins, such as histone acetyltransferases and transcription factors, is essential for elucidating HDAC2′s role in gene regulation and potential therapeutic targeting in various diseases.

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Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Histone Deacetylase 2 (HDAC2) Antibody (3F3) has 32 citations in a variety of scientific publications.

Primary antibodies like Anti-Histone Deacetylase 2 (HDAC2) Antibody (3F3) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Histone Deacetylase 2 (HDAC2) Antibody (3F3) Specifications

Alternate Product Name: HDAC2

Product Clone Name: 3F3

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 473-488

Epitope Target: HDAC2

Epitope Species: human

Product Reactivity/Detection: HDAC2

Species Reactivity/Detection: mouse, rat, human, bovine

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P)

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 32 citations in various scientific publications

Available Conjugates/Forms for Histone Deacetylase 2 (HDAC2) Antibody (3F3): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin

The preferred Histone Deacetylase 2 antibody is Histone Deacetylase 2 Antibody (C-8): sc-9959.