HCN3 Antibody (TLL6C5): sc-58621
- HCN3 Antibody (TLL6C5) is a rat monoclonal IgG1 HCN3 antibody provided at 200 µg/ml
- raised against a synthetic peptide of HCN3 of mouse origin
- HCN3 Antibody (TLL6C5) is recommended for detection of HCN3 of mouse, rat, human, bovine and canine origin by WB and IP
- Anti-HCN3 Antibody (TLL6C5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for HCN3 Antibody (TLL6C5). This work is in progress.
QUICK LINKS
HCN3 Antibody (TLL6C5) is a rat monoclonal IgG1 antibody that detects HCN3 protein of mouse, rat, human, bovine, and canine origin by western blotting (WB) and immunoprecipitation (IP). Anti-HCN3 antibody (TLL6C5) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. HCN3 is a member of the hyperpolarization-activated, cyclic nucleotide-binding channel family, which plays a crucial role in generating rhythmic electrical activity in excitable tissues such as the heart and brain. These channels are activated by the binding of intracellular cyclic nucleotides, which allows them to respond to changes in cellular signaling. HCN3 is characterized by a distinctive S4 segment that contains a series of positively charged amino acids, functioning as a voltage sensor that is essential for channel activation. Expression of HCN3 is predominantly found in the brain, particularly in regions such as the hypothalamus, where HCN3 contributes to the regulation of neuronal excitability and rhythmic firing patterns. Understanding the function and distribution of HCN3 is vital for elucidating its role in physiological processes and potential implications in various neurological and cardiac disorders.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HCN3 Antibody (TLL6C5) | sc-58621 | 200 µg/ml | $322.00 | |||
HCN3 Antibody (TLL6C5) AC | sc-58621 AC | 500 µg/ml, 25% agarose | $424.00 | |||
HCN3 Antibody (TLL6C5) HRP | sc-58621 HRP | 200 µg/ml | $322.00 | |||
HCN3 Antibody (TLL6C5) FITC | sc-58621 FITC | 200 µg/ml | $336.00 | |||
HCN3 Antibody (TLL6C5) PE | sc-58621 PE | 200 µg/ml | $349.00 | |||
HCN3 Antibody (TLL6C5) Alexa Fluor® 488 | sc-58621 AF488 | 200 µg/ml | $364.00 | |||
HCN3 Antibody (TLL6C5) Alexa Fluor® 546 | sc-58621 AF546 | 200 µg/ml | $364.00 | |||
HCN3 Antibody (TLL6C5) Alexa Fluor® 594 | sc-58621 AF594 | 200 µg/ml | $364.00 | |||
HCN3 Antibody (TLL6C5) Alexa Fluor® 647 | sc-58621 AF647 | 200 µg/ml | $364.00 | |||
HCN3 Antibody (TLL6C5) Alexa Fluor® 680 | sc-58621 AF680 | 200 µg/ml | $364.00 | |||
HCN3 Antibody (TLL6C5) Alexa Fluor® 790 | sc-58621 AF790 | 200 µg/ml | $364.00 |