Date published: 2025-11-24

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HCN4 Antibodies

Santa Cruz Biotechnology offers a broad range of HCN4 monoclonal antibodies for research focused on understanding HCN4 protein function. The monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). HCN4, or hyperpolarization-activated cyclic nucleotide-gated channel 4, is crucial for regulating cardiac pacemaker activity and neuronal excitability. HCN4 plays a significant role in controlling heart rate and rhythm, making it an essential target for studies related to cardiac function and arrhythmias. Research involving HCN4 can provide insights into various cardiovascular diseases and potential therapeutic approaches. Investigating HCN4 expression and function helps advance understanding of cardiac rhythm disorders and their treatments. Studying HCN4 channels contributes to developing new therapeutic strategies for cardiac arrhythmias. Exploring HCN4's role in neuronal function provides valuable insights into nervous system regulation. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing scientific understanding of cardiovascular and neurological health.

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HCN4 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

HCN4 Antibody (SHG 1E5)

sc-58622rat IgG11048-1085 (h)WB, IP, IFm, r, h
6
(6)

HCN4 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HCN4 CRISPR/Cas9 KO Plasmid (h)

sc-402293hGene KnockoutGFP0
(0)

HCN4 HDR Plasmid (h)

sc-402293-HDRhHomology Directed RepairPuromycin0
(0)

HCN4 Double Nickase Plasmid (h)

sc-402293-NIChGene KnockoutPuromycin0
(0)

HCN4 Double Nickase Plasmid (h2)

sc-402293-NIC-2hGene KnockoutPuromycin0
(0)

HCN4 CRISPR/Cas9 KO Plasmid (m)

sc-436048mGene KnockoutGFP0
(0)

HCN4 HDR Plasmid (m)

sc-436048-HDRmHomology Directed RepairPuromycin0
(0)

HCN4 Double Nickase Plasmid (m)

sc-436048-NICmGene KnockoutPuromycin0
(0)

HCN4 Double Nickase Plasmid (m2)

sc-436048-NIC-2mGene KnockoutPuromycin0
(0)

HCN4 CRISPR Activation Products

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HCN4 CRISPR Activation Plasmid (h)

sc-402293-ACThGene ActivationPuro, Blast, Hygro0
(0)

HCN4 CRISPR Activation Plasmid (h2)

sc-402293-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

HCN4 Lentiviral Activation Particles (h)

sc-402293-LAChGene ActivationPuro, Blast, Hygro0
(0)

HCN4 Lentiviral Activation Particles (h2)

sc-402293-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

HCN4 CRISPR Activation Plasmid (m)

sc-436048-ACTmGene ActivationPuro, Blast, Hygro0
(0)

HCN4 CRISPR Activation Plasmid (m2)

sc-436048-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

HCN4 Lentiviral Activation Particles (m)

sc-436048-LACmGene ActivationPuro, Blast, Hygro0
(0)

HCN4 Lentiviral Activation Particles (m2)

sc-436048-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

HCN4 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HCN4 siRNA (h)

sc-42473hGene SilencingN/A0
(0)

HCN4 shRNA Plasmid (h)

sc-42473-SHhGene SilencingPuromycin0
(0)

HCN4 shRNA (h) Lentiviral Particles

sc-42473-VhGene SilencingPuromycin0
(0)

HCN4 siRNA (m)

sc-42474mGene SilencingN/A0
(0)

HCN4 shRNA Plasmid (m)

sc-42474-SHmGene SilencingPuromycin0
(0)

HCN4 shRNA (m) Lentiviral Particles

sc-42474-VmGene SilencingPuromycin0
(0)

HCN4 siRNA (r)

sc-270294rGene SilencingN/A0
(0)

HCN4 shRNA Plasmid (r)

sc-270294-SHrGene SilencingPuromycin0
(0)

HCN4 shRNA (r) Lentiviral Particles

sc-270294-VrGene SilencingPuromycin0
(0)