GTPBP9 Antibody (F-7): sc-390704

GTPBP9 Antibody (F-7) is a mouse monoclonal IgG1 antibody that detects GTP-binding protein 9 (GTPBP9) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). GTPBP9, also known as Obg-like ATPase 1 (OLA1), is a 396 amino acid protein that plays a crucial role in cellular processes by functioning as a GTPase and ATPase, with a notable preference for ATP binding over GTP. The protein′s unique structure includes a C-terminal TGS domain responsible for ligand binding and an N-terminal G domain that interacts with nucleotides, essential for GTPBP9 activity. GTPBP9 is expressed in three isoforms due to alternative splicing, allowing for functional diversity in cellular roles. A specific amino acid substitution enables GTPBP9 to bind ATP preferentially over GTP, highlighting distinct regulatory mechanisms compared to other GTPases and making GTPBP9 an important target for research in cellular signaling and metabolic regulation. Anti-GTPBP9 antibody (F-7) serves as an invaluable tool for researchers studying this protein′s intricate functions in various biological contexts.

The preferred GTPBP9 antibody is GTPBP9 Antibody (G-6): sc-393946.