GS27 Antibody (GS27): sc-130562

GS27 Antibody (GS27) is a mouse monoclonal IgG1 antibody that detects GS27 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). GS27 is a crucial member of the SNARE protein family, playing a vital role in the intracellular transport of proteins between the endoplasmic reticulum and the Golgi apparatus, as well as within Golgi subcompartments. GS27 (GS27) antibody facilitates the study of vesicular transport processes, where GS27 enables the fusion of vesicles with target membranes by forming stable complexes with other SNARE proteins. Proper functioning of GS27 is essential for maintaining cellular homeostasis and ensuring proteins reach their correct destinations, which is particularly important for membrane-directed proteins that require precise localization to perform their functions. The human GS27 gene is located on chromosome 17q21, in proximity to a locus associated with familial essential hypertension, suggesting that variations in this gene may contribute to the pathophysiology of this condition. Anti-GS27 antibody (GS27) serves as an invaluable tool for researchers studying protein transport mechanisms and their implications in health and disease.

The preferred GS27 antibody is GS27 Antibody (F-6): sc-390261.