GROα/β/γ Antibody (A-6): sc-365870

GROα/β/γ Antibody (A-6) is a mouse monoclonal IgG2b kappa light chain antibody that detects GROα/β/γ protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). GROα/β/γ Antibody (A-6) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. GRO proteins, which belong to the C-X-C chemokine subfamily, are crucial for regulating cell motility and growth, acting as potent neutrophil chemoattractants and mediators of angiogenesis. These proteins are secreted in response to inflammatory stimuli and play a significant role in the immune response, particularly in recruiting immune cells to sites of infection or injury. GROα, β, and γ are involved in the progression of various diseases, including cancer, where these proteins may influence the transition of melanocytes to malignant melanoma. Understanding GRO protein function is essential for developing therapeutic strategies targeting inflammatory and oncogenic pathways, making anti-GROα/β/γ antibody (A-6) a valuable tool for researchers studying these critical biological processes.

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GROα/β/γ Antibody (A-6) References:

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5. Gene Expression of CXCL1 (GRO-α) and EGF by Platelets in Myeloproliferative Neoplasms.  |  Collinson, RJ., et al. 2020. Hemasphere. 4: e490. PMID: 33134870
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Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-GROα/β/γ Antibody (A-6) has 8 citations in a variety of scientific publications.

Primary antibodies like Anti-GROα/β/γ Antibody (A-6) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

GROα/β/γ Antibody (A-6) Specifications

Alternate Product Name: GROα/β/γ

Product Clone Name: A-6

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2b kappa light chain

Amino Acids: 1-100

Epitope Target: MIP-2

Epitope Species: mouse

Product Reactivity/Detection: GROα of mouse, rat and human origin, GROβ and GROγ of human origin, and MIP-2 and Cxcl3 of mouse origin and the corresponding rat homologs

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 200 µg IgG_2b kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 8 citations in various scientific publications

Available Conjugates/Forms for GROα/β/γ Antibody (A-6): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin